Round cell variant of myxoid liposarcoma in a Japanese Macaque (Macaca fuscata)

Ho Jeong Kwon, M. S. Park, D. Y. Kim, D. Y. Cho, B. I. Yoon, N. S. Shin, D. Y. Kim

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A 5-year-old, female, Japanese Macaque (Macaca fuscata) was diagnosed with round cell variant of myxoid liposarcoma. At necropsy, multifocal to coalescing, reddish tan to white nodules, ranging from 0.5 to 1 cm in diameter, were noted throughout the omentum and retroperitoneum. Similar neoplastic nodules were also present in diaphragm, abdominal wall, and on hepatic capsule. Microscopically, neoplastic masses consisted of round to polyhedral cells, which had round, often eccentric nuclei and abundant eosinophilic granular and microvacuolated cytoplasm; Oil red O staining demonstrated large numbers of lipid droplets in the cytoplasm. Ultrastructurally, the cytoplasm of the tumor cells was packed with occasional lipid vacuoles and numerous enlarged mitochondria. Immunohistochemistry revealed tumor cells were positive for vimentin, while negative to cytokeratin, actin, and Factor VIII-related antigen. To the authors' knowledge, this is the first report of round-cell variant of myxoid liposarcoma in nonhuman primate.

Original languageEnglish
Pages (from-to)229-232
Number of pages4
JournalVeterinary Pathology
Volume44
Issue number2
DOIs
Publication statusPublished - 2007 Mar 1

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Myxoid Liposarcoma
Macaca fuscata
Macaca
cytoplasm
Cytoplasm
omentum
factor VIII
vimentin
diaphragm
cells
lipids
droplets
actin
immunohistochemistry
vacuoles
necropsy
Primates
mitochondria
Omentum
antigens

All Science Journal Classification (ASJC) codes

  • veterinary(all)

Cite this

Kwon, H. J., Park, M. S., Kim, D. Y., Cho, D. Y., Yoon, B. I., Shin, N. S., & Kim, D. Y. (2007). Round cell variant of myxoid liposarcoma in a Japanese Macaque (Macaca fuscata). Veterinary Pathology, 44(2), 229-232. https://doi.org/10.1354/vp.44-2-229
Kwon, Ho Jeong ; Park, M. S. ; Kim, D. Y. ; Cho, D. Y. ; Yoon, B. I. ; Shin, N. S. ; Kim, D. Y. / Round cell variant of myxoid liposarcoma in a Japanese Macaque (Macaca fuscata). In: Veterinary Pathology. 2007 ; Vol. 44, No. 2. pp. 229-232.
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Kwon, HJ, Park, MS, Kim, DY, Cho, DY, Yoon, BI, Shin, NS & Kim, DY 2007, 'Round cell variant of myxoid liposarcoma in a Japanese Macaque (Macaca fuscata)', Veterinary Pathology, vol. 44, no. 2, pp. 229-232. https://doi.org/10.1354/vp.44-2-229

Round cell variant of myxoid liposarcoma in a Japanese Macaque (Macaca fuscata). / Kwon, Ho Jeong; Park, M. S.; Kim, D. Y.; Cho, D. Y.; Yoon, B. I.; Shin, N. S.; Kim, D. Y.

In: Veterinary Pathology, Vol. 44, No. 2, 01.03.2007, p. 229-232.

Research output: Contribution to journalArticle

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