Safety and effectiveness of sirolimus-eluting stent implantation for in-stent restenosis of the unprotected left main coronary artery

Hyun Sook Kim, Young Hak Kim, Seung Whan Lee, Duk Woo Park, Cheol Whan Lee, Myeong Ki Hong, Jae Joong Kim, Seong Wook Park, Seung Jung Park

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4 Citations (Scopus)

Abstract

The present study examined the alternative treatment of sirolimus-eluting stent (SES) implantation for in-stent restenosis (ISR) of the unprotected left main coronary artery (LMCA). Twelve patients underwent SES deployment for bare-metal ISR in the LMCA. ISR were 24 ± 11 mm in length and located at the ostial (n = 1) and distal (n = 11) portion of LMCA. Bifurcation lesions were treated with one of three techniques: the stent crossing the left circumflex artery (n = 7), kissing stenting (n = 2) or the Crush technique (n = 2). All procedures were performed using intravascular ultrasound guidance. Periprocedural CK-MB elevation ≥ 3 times normal occurred in 2 patients. There were no cases of significant narrowing in the left circumflex artery after the procedure. At the one-year follow-up, one patient died and there were no incidents of myocardial infarction or target lesion revascularization. The present study suggests that SES implantation may be a feasible therapeutic option for treating ISR in unprotected LMCA.

Original languageEnglish
Pages (from-to)118-120
Number of pages3
JournalInternational Journal of Cardiology
Volume124
Issue number1
DOIs
Publication statusPublished - 2008 Feb 20

Bibliographical note

Funding Information:
This study was partly supported by the Cardio Vascular Research Foundation, Seoul, Korea, a grant of the Korea Health 21 R&D Project, Ministry of Health and Welfare, Korea (0412-CR02-0704-0001), and Asan Institute for Life Sciences, Seoul, Korea (2004-361, 2005-361).

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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