Salicylic acid peels versus Jessner's solution for acne vulgaris: A comparative study

Byung Gi Bae, Chang Ook Park, Hyoseung Shin, Soo Hyun Lee, Yun Sun Lee, Sang Ju Lee, Kee Yang Chung, Kwang Hoon Lee, Ju Hee Lee

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background Salicylic acid was recently formulated in a hydroethanolic vehicle at a concentration of 20% to 30%. Salicylic acid has strong comedolytic effects because of its lipophilic nature. Objective To compare the therapeutic efficacy and tolerability of salicylic acid peels with those of Jessner's solution peels in patients with acne vulgaris. Methods Thirteen patients (13 men; mean age 22.6, range 20-28) with facial acne were enrolled. Jessner's solution was applied to one side of each patient's face and 30% salicylic acid to the other in three sessions at 2-week intervals. A blinded investigator counted noninflammatory and inflammatory lesions before treatment and 2 weeks after each treatment. Results Inflammatory and noninflammatory acne lesion counts decreased in proportion to the duration of treatment. Inflammatory acne lesion counts did not differ significantly between salicylic acid and Jessner's solution peels, although in terms of noninflammatory acne lesion counts, sites treated with salicylic acid showed significant improvement (p =.04), whereas those treated with Jessner's solution did not. Conclusion We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne.

Original languageEnglish
Pages (from-to)248-253
Number of pages6
JournalDermatologic Surgery
Volume39
Issue number2
DOIs
Publication statusPublished - 2013 Feb 1

All Science Journal Classification (ASJC) codes

  • Surgery
  • Dermatology

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    Bae, B. G., Park, C. O., Shin, H., Lee, S. H., Lee, Y. S., Lee, S. J., Chung, K. Y., Lee, K. H., & Lee, J. H. (2013). Salicylic acid peels versus Jessner's solution for acne vulgaris: A comparative study. Dermatologic Surgery, 39(2), 248-253. https://doi.org/10.1111/dsu.12018