Scalable multiplexed drug-combination screening platforms using 3D microtumor model for precision medicine

Zhixiong Zhang, Sumithra Urs, Yu Chih Chen, Karnik Bipin Sangani, Diane Simeone, Euisik Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Drug combination treatment has emerged as a standard of care for many diseases including cancer. The chance of finding an appropriate drug combination for a certain patient increases with more target compounds under investigation. However, experimental complexity and cost grow exponentially as the number of drug candidates increases. Here, we report a scalable, easy-to-handle, high-throughput drug combination screening platform which enables screening of any possible dual-drug combinations from 8 different drugs with various concentration gradients.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages643-644
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 2016 Oct 92016 Oct 13

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period16/10/916/10/13

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Fingerprint Dive into the research topics of 'Scalable multiplexed drug-combination screening platforms using 3D microtumor model for precision medicine'. Together they form a unique fingerprint.

Cite this