Schedules for Pneumococcal Vaccination of Preterm Infants: An RCT

A. Kent, S. N. Ladhani, N. J. Andrews, T. Scorrer, A. J. Pollard, P. Clarke, S. M. Hughes, C. Heal, E. Menson, J. Chang, P. Satodia, A. C. Collinson, S. N. Faust, D. Goldblatt, E. Miller, P. T. Heath

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Abstract

BACKGROUND AND OBJECTIVE: Premature infants have a higher risk of invasive pneumococcal disease and are more likely to have lower vaccine responses compared with term infants. Increasingly, immunization schedules are including a reduced, 2-dose, pneumococcal conjugate vaccine priming schedule. Our goal was to assess the immunogenicity of 3 commonly used 13-valent pneumococcal conjugate vaccine (PCV13) priming schedules in premature infants and their response to a 12-month booster dose. METHODS: Premature infants (
Original languageEnglish
Title of host publicationPEDIATRICS
Pagese20153945-e20153945
DOIs
Publication statusPublished - 2016 Sep 1

Publication series

NamePEDIATRICS
Volume138

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Kent, A., Ladhani, S. N., Andrews, N. J., Scorrer, T., Pollard, A. J., Clarke, P., Hughes, S. M., Heal, C., Menson, E., Chang, J., Satodia, P., Collinson, A. C., Faust, S. N., Goldblatt, D., Miller, E., & Heath, P. T. (2016). Schedules for Pneumococcal Vaccination of Preterm Infants: An RCT. In PEDIATRICS (pp. e20153945-e20153945). (PEDIATRICS; Vol. 138). https://doi.org/10.1542/peds.2015-3945