Secondary endoscopic submucosal dissection for locally recurrent or incompletely resected gastric neoplasms

Da Hyun Jung, Young Hoon Youn, Jie-Hyun Kim, Jae Jun Park, HyoJin Park

Research output: Contribution to journalArticle

Abstract

AIM To investigate the feasibility and safety of secondary endoscopic submucosal dissection (ESD) for residual or locally recurrent gastric tumors. METHODS Between 2010 and 2017, 1623 consecutive patients underwent ESD for gastric neoplasms at a single tertiary referral center. Among these, 28 patients underwent secondary ESD for a residual or locally recurrent tumor. Our analysis compared clinicopathologic factors between primary ESD and secondary ESD groups. RESULTS The en bloc resection and curative rate of resection of secondary ESD were 92.9% and 89.3%, respectively. The average procedure time of secondary ESD was significantly longer than primary ESD (78.2 min vs 55.1 min, P = 0.004), and the adverse events rate was not significantly different but trended slightly higher in the secondary ESD group compared to the primary ESD group (10.7% vs 3.8%, P = 0.095). Patients who received secondary ESD had favorable outcomes without severe adverse events. During a mean followup period, no local recurrence occurred in patients who received secondary ESD. CONCLUSION Secondary ESD of residual or locally recurrent gastric tumors appears to be a feasible and curative treatment though it requires greater technical efficiency and longer procedure time.

Original languageEnglish
Pages (from-to)3776-3785
Number of pages10
JournalWorld Journal of Gastroenterology
Volume24
Issue number33
DOIs
Publication statusPublished - 2018 Sep 7

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Stomach Neoplasms
Endoscopic Mucosal Resection
Stomach
Neoplasms
Tertiary Care Centers
Safety
Recurrence

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

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abstract = "AIM To investigate the feasibility and safety of secondary endoscopic submucosal dissection (ESD) for residual or locally recurrent gastric tumors. METHODS Between 2010 and 2017, 1623 consecutive patients underwent ESD for gastric neoplasms at a single tertiary referral center. Among these, 28 patients underwent secondary ESD for a residual or locally recurrent tumor. Our analysis compared clinicopathologic factors between primary ESD and secondary ESD groups. RESULTS The en bloc resection and curative rate of resection of secondary ESD were 92.9{\%} and 89.3{\%}, respectively. The average procedure time of secondary ESD was significantly longer than primary ESD (78.2 min vs 55.1 min, P = 0.004), and the adverse events rate was not significantly different but trended slightly higher in the secondary ESD group compared to the primary ESD group (10.7{\%} vs 3.8{\%}, P = 0.095). Patients who received secondary ESD had favorable outcomes without severe adverse events. During a mean followup period, no local recurrence occurred in patients who received secondary ESD. CONCLUSION Secondary ESD of residual or locally recurrent gastric tumors appears to be a feasible and curative treatment though it requires greater technical efficiency and longer procedure time.",
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Secondary endoscopic submucosal dissection for locally recurrent or incompletely resected gastric neoplasms. / Jung, Da Hyun; Youn, Young Hoon; Kim, Jie-Hyun; Park, Jae Jun; Park, HyoJin.

In: World Journal of Gastroenterology, Vol. 24, No. 33, 07.09.2018, p. 3776-3785.

Research output: Contribution to journalArticle

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