Sedation for interventional gastrointestinal endoscopic procedures: Are we overlooking the "pain"?

Seokyung Shin, Sang Kil Lee, Kyung Tae Min, Hyun Ju Kim, Chan Hyuk Park, Young Chul Yoo

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background Although interventional gastrointestinal (GI) endoscopic procedures are known to cause greater pain and discomfort than diagnostic procedures, the efficacy of adequate pain control or the difference in pain and amount of analgesic required according to type of intervention is not well known. This study was done to investigate the safety and efficacy of combining fentanyl with propofol for interventional GI endoscopic procedures and determine whether this method is superior to propofol monosedation. Methods The data of 810 patients that underwent interventional GI endoscopic procedures under sedation with either propofol alone (Group P, n = 499) or propofol/ fentanyl (Group PF, n = 311) at a single tertiary-care hospital between May 2012 and December 2012 were retrospectively reviewed. Rates of respiratory and cardiovascular events, propofol and fentanyl requirements, and risk factors of respiratory events of the two groups were analyzed. Results The incidence of respiratory events (P = 0.001), number of cases in which the procedure had to be interrupted for assisted mask bagging (P = 0.044), and propofol infusion rates were significantly lower in Group PF compared to Group P (p < 0.0001). The amount of fentanyl required for diagnostic procedures was significantly lower than that for interventional procedures (p < 0.001). Patients of Group PF showed a lower risk of developing respiratory events compared to Group P (OR 0.224, 95 % CI 0.069-0.724). Conclusions Combining fentanyl with propofol seems to reduce the risk of respiratory events compared with propofol monosedation during GI endoscopic procedures by providing effective analgesia.

Original languageEnglish
Pages (from-to)100-107
Number of pages8
JournalSurgical endoscopy
Volume28
Issue number1
DOIs
Publication statusPublished - 2014 Jan

Fingerprint

Propofol
Pain
Fentanyl
Tertiary Healthcare
Respiratory Rate
Masks
Tertiary Care Centers
Analgesia
Analgesics
Safety
Incidence

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Shin, Seokyung ; Lee, Sang Kil ; Min, Kyung Tae ; Kim, Hyun Ju ; Park, Chan Hyuk ; Yoo, Young Chul. / Sedation for interventional gastrointestinal endoscopic procedures : Are we overlooking the "pain"?. In: Surgical endoscopy. 2014 ; Vol. 28, No. 1. pp. 100-107.
@article{e10e50804e294e56a46eb70272c0bac1,
title = "Sedation for interventional gastrointestinal endoscopic procedures: Are we overlooking the {"}pain{"}?",
abstract = "Background Although interventional gastrointestinal (GI) endoscopic procedures are known to cause greater pain and discomfort than diagnostic procedures, the efficacy of adequate pain control or the difference in pain and amount of analgesic required according to type of intervention is not well known. This study was done to investigate the safety and efficacy of combining fentanyl with propofol for interventional GI endoscopic procedures and determine whether this method is superior to propofol monosedation. Methods The data of 810 patients that underwent interventional GI endoscopic procedures under sedation with either propofol alone (Group P, n = 499) or propofol/ fentanyl (Group PF, n = 311) at a single tertiary-care hospital between May 2012 and December 2012 were retrospectively reviewed. Rates of respiratory and cardiovascular events, propofol and fentanyl requirements, and risk factors of respiratory events of the two groups were analyzed. Results The incidence of respiratory events (P = 0.001), number of cases in which the procedure had to be interrupted for assisted mask bagging (P = 0.044), and propofol infusion rates were significantly lower in Group PF compared to Group P (p < 0.0001). The amount of fentanyl required for diagnostic procedures was significantly lower than that for interventional procedures (p < 0.001). Patients of Group PF showed a lower risk of developing respiratory events compared to Group P (OR 0.224, 95 {\%} CI 0.069-0.724). Conclusions Combining fentanyl with propofol seems to reduce the risk of respiratory events compared with propofol monosedation during GI endoscopic procedures by providing effective analgesia.",
author = "Seokyung Shin and Lee, {Sang Kil} and Min, {Kyung Tae} and Kim, {Hyun Ju} and Park, {Chan Hyuk} and Yoo, {Young Chul}",
year = "2014",
month = "1",
doi = "10.1007/s00464-013-3133-y",
language = "English",
volume = "28",
pages = "100--107",
journal = "Surgical Endoscopy",
issn = "0930-2794",
publisher = "Springer New York",
number = "1",

}

Sedation for interventional gastrointestinal endoscopic procedures : Are we overlooking the "pain"? / Shin, Seokyung; Lee, Sang Kil; Min, Kyung Tae; Kim, Hyun Ju; Park, Chan Hyuk; Yoo, Young Chul.

In: Surgical endoscopy, Vol. 28, No. 1, 01.2014, p. 100-107.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Sedation for interventional gastrointestinal endoscopic procedures

T2 - Are we overlooking the "pain"?

AU - Shin, Seokyung

AU - Lee, Sang Kil

AU - Min, Kyung Tae

AU - Kim, Hyun Ju

AU - Park, Chan Hyuk

AU - Yoo, Young Chul

PY - 2014/1

Y1 - 2014/1

N2 - Background Although interventional gastrointestinal (GI) endoscopic procedures are known to cause greater pain and discomfort than diagnostic procedures, the efficacy of adequate pain control or the difference in pain and amount of analgesic required according to type of intervention is not well known. This study was done to investigate the safety and efficacy of combining fentanyl with propofol for interventional GI endoscopic procedures and determine whether this method is superior to propofol monosedation. Methods The data of 810 patients that underwent interventional GI endoscopic procedures under sedation with either propofol alone (Group P, n = 499) or propofol/ fentanyl (Group PF, n = 311) at a single tertiary-care hospital between May 2012 and December 2012 were retrospectively reviewed. Rates of respiratory and cardiovascular events, propofol and fentanyl requirements, and risk factors of respiratory events of the two groups were analyzed. Results The incidence of respiratory events (P = 0.001), number of cases in which the procedure had to be interrupted for assisted mask bagging (P = 0.044), and propofol infusion rates were significantly lower in Group PF compared to Group P (p < 0.0001). The amount of fentanyl required for diagnostic procedures was significantly lower than that for interventional procedures (p < 0.001). Patients of Group PF showed a lower risk of developing respiratory events compared to Group P (OR 0.224, 95 % CI 0.069-0.724). Conclusions Combining fentanyl with propofol seems to reduce the risk of respiratory events compared with propofol monosedation during GI endoscopic procedures by providing effective analgesia.

AB - Background Although interventional gastrointestinal (GI) endoscopic procedures are known to cause greater pain and discomfort than diagnostic procedures, the efficacy of adequate pain control or the difference in pain and amount of analgesic required according to type of intervention is not well known. This study was done to investigate the safety and efficacy of combining fentanyl with propofol for interventional GI endoscopic procedures and determine whether this method is superior to propofol monosedation. Methods The data of 810 patients that underwent interventional GI endoscopic procedures under sedation with either propofol alone (Group P, n = 499) or propofol/ fentanyl (Group PF, n = 311) at a single tertiary-care hospital between May 2012 and December 2012 were retrospectively reviewed. Rates of respiratory and cardiovascular events, propofol and fentanyl requirements, and risk factors of respiratory events of the two groups were analyzed. Results The incidence of respiratory events (P = 0.001), number of cases in which the procedure had to be interrupted for assisted mask bagging (P = 0.044), and propofol infusion rates were significantly lower in Group PF compared to Group P (p < 0.0001). The amount of fentanyl required for diagnostic procedures was significantly lower than that for interventional procedures (p < 0.001). Patients of Group PF showed a lower risk of developing respiratory events compared to Group P (OR 0.224, 95 % CI 0.069-0.724). Conclusions Combining fentanyl with propofol seems to reduce the risk of respiratory events compared with propofol monosedation during GI endoscopic procedures by providing effective analgesia.

UR - http://www.scopus.com/inward/record.url?scp=84892994641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892994641&partnerID=8YFLogxK

U2 - 10.1007/s00464-013-3133-y

DO - 10.1007/s00464-013-3133-y

M3 - Article

C2 - 23959522

AN - SCOPUS:84892994641

VL - 28

SP - 100

EP - 107

JO - Surgical Endoscopy

JF - Surgical Endoscopy

SN - 0930-2794

IS - 1

ER -