Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells

Eun Kyung Lim; Jaemoon Yang; Jin Suck Suh; Yong Min Huh; Seungjoo Haam

doi:10.1039/b912149h

Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells

Eun Kyung Lim, Jaemoon Yang, Jin Suck Suh, Yong Min Huh, Seungjoo Haam

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Self-labeled magneto nanoprobes (SLMNs) were synthesized for one-step labeling of human mesenchymal stem cells (hMSCs) via non-invasive magnetic resonance (MR) image tracking. The surface of superparamagnetic nanocrystals (SMNCs) were enveloped by tri-aminated polysorbate 80 (TP80) not only for enhancement of the affinity for hMSCs, but also to achieve increased colloidal stability in the aqueous phase by the nanoemulsion method. The synthesized SLMNs exhibited excellent labeling efficiency of hMSCs and produced highly sensitive MR signals as well as safe cell cytotoxicity.

Original language	English
Pages (from-to)	8958-8963
Number of pages	6
Journal	Journal of Materials Chemistry
Volume	19
Issue number	47
DOIs	https://doi.org/10.1039/b912149h
Publication status	Published - 2009

All Science Journal Classification (ASJC) codes

Chemistry(all)
Materials Chemistry

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abstract = "Self-labeled magneto nanoprobes (SLMNs) were synthesized for one-step labeling of human mesenchymal stem cells (hMSCs) via non-invasive magnetic resonance (MR) image tracking. The surface of superparamagnetic nanocrystals (SMNCs) were enveloped by tri-aminated polysorbate 80 (TP80) not only for enhancement of the affinity for hMSCs, but also to achieve increased colloidal stability in the aqueous phase by the nanoemulsion method. The synthesized SLMNs exhibited excellent labeling efficiency of hMSCs and produced highly sensitive MR signals as well as safe cell cytotoxicity.",

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AU - Lim, Eun Kyung

AU - Yang, Jaemoon

AU - Suh, Jin Suck

AU - Huh, Yong Min

AU - Haam, Seungjoo

PY - 2009

Y1 - 2009

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AB - Self-labeled magneto nanoprobes (SLMNs) were synthesized for one-step labeling of human mesenchymal stem cells (hMSCs) via non-invasive magnetic resonance (MR) image tracking. The surface of superparamagnetic nanocrystals (SMNCs) were enveloped by tri-aminated polysorbate 80 (TP80) not only for enhancement of the affinity for hMSCs, but also to achieve increased colloidal stability in the aqueous phase by the nanoemulsion method. The synthesized SLMNs exhibited excellent labeling efficiency of hMSCs and produced highly sensitive MR signals as well as safe cell cytotoxicity.

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Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells

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