Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells

Eun Kyung Lim, Jaemoon Yang, Jin Suck Suh, Yong Min Huh, Seungjoo Haam

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Self-labeled magneto nanoprobes (SLMNs) were synthesized for one-step labeling of human mesenchymal stem cells (hMSCs) via non-invasive magnetic resonance (MR) image tracking. The surface of superparamagnetic nanocrystals (SMNCs) were enveloped by tri-aminated polysorbate 80 (TP80) not only for enhancement of the affinity for hMSCs, but also to achieve increased colloidal stability in the aqueous phase by the nanoemulsion method. The synthesized SLMNs exhibited excellent labeling efficiency of hMSCs and produced highly sensitive MR signals as well as safe cell cytotoxicity.

Original languageEnglish
Pages (from-to)8958-8963
Number of pages6
JournalJournal of Materials Chemistry
Volume19
Issue number47
DOIs
Publication statusPublished - 2009

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells'. Together they form a unique fingerprint.

Cite this