Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells

Eun Kyung Lim, Jaemoon Yang, Jinsuck Suh, yongmin Huh, Seungjoo Haam

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18 Citations (Scopus)


Self-labeled magneto nanoprobes (SLMNs) were synthesized for one-step labeling of human mesenchymal stem cells (hMSCs) via non-invasive magnetic resonance (MR) image tracking. The surface of superparamagnetic nanocrystals (SMNCs) were enveloped by tri-aminated polysorbate 80 (TP80) not only for enhancement of the affinity for hMSCs, but also to achieve increased colloidal stability in the aqueous phase by the nanoemulsion method. The synthesized SLMNs exhibited excellent labeling efficiency of hMSCs and produced highly sensitive MR signals as well as safe cell cytotoxicity.

Original languageEnglish
Pages (from-to)8958-8963
Number of pages6
JournalJournal of Materials Chemistry
Issue number47
Publication statusPublished - 2009 Dec 1


All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Chemistry

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