Self-powered deep brain stimulation via a flexible PIMNT energy harvester

Geon Tae Hwang, Youngsoo Kim, Jeong Ho Lee, Sekwon Oh, Chang Kyu Jeong, Dae Yong Park, Jungho Ryu, Hyuksang Kwon, Sang Goo Lee, Boyoung Joung, Daesoo Kim, Keon Jae Lee

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

Deep brain stimulation (DBS) is widely used for neural prosthetics and brain-computer interfacing. Thus far in vivo implantation of a battery has been a prerequisite to supply the necessary power. Although flexible energy harvesters have recently emerged as alternatives to batteries, they generate insufficient energy for operating brain stimulation. Herein, we report a high performance flexible piezoelectric energy harvester by enabling self-powered DBS in mice. This device adopts an indium modified crystalline Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 (PIMNT) thin film on a plastic substrate to transform tiny mechanical motions to electricity. With slight bending, it generates an extremely high current reaching 0.57 mA, which satisfies the high threshold current for real-time DBS of the motor cortex and thereby could efficiently induce forearm movements in mice. The PIMNT based flexible energy harvester could open a new avenue for future in vivo healthcare technology using self-powered biomedical devices.

Original languageEnglish
Pages (from-to)2677-2684
Number of pages8
JournalEnergy and Environmental Science
Volume8
Issue number9
DOIs
Publication statusPublished - 2015 Sep 1

Fingerprint

Harvesters
brain
Brain
energy
indium
Indium
Prosthetics
health care
electricity
transform
Electricity
plastic
Plastics
Crystalline materials
substrate
Thin films
Substrates

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Renewable Energy, Sustainability and the Environment
  • Nuclear Energy and Engineering
  • Pollution

Cite this

Hwang, G. T., Kim, Y., Lee, J. H., Oh, S., Jeong, C. K., Park, D. Y., ... Lee, K. J. (2015). Self-powered deep brain stimulation via a flexible PIMNT energy harvester. Energy and Environmental Science, 8(9), 2677-2684. https://doi.org/10.1039/c5ee01593f
Hwang, Geon Tae ; Kim, Youngsoo ; Lee, Jeong Ho ; Oh, Sekwon ; Jeong, Chang Kyu ; Park, Dae Yong ; Ryu, Jungho ; Kwon, Hyuksang ; Lee, Sang Goo ; Joung, Boyoung ; Kim, Daesoo ; Lee, Keon Jae. / Self-powered deep brain stimulation via a flexible PIMNT energy harvester. In: Energy and Environmental Science. 2015 ; Vol. 8, No. 9. pp. 2677-2684.
@article{c087e9fe0bea41b0a1de9df7d374071c,
title = "Self-powered deep brain stimulation via a flexible PIMNT energy harvester",
abstract = "Deep brain stimulation (DBS) is widely used for neural prosthetics and brain-computer interfacing. Thus far in vivo implantation of a battery has been a prerequisite to supply the necessary power. Although flexible energy harvesters have recently emerged as alternatives to batteries, they generate insufficient energy for operating brain stimulation. Herein, we report a high performance flexible piezoelectric energy harvester by enabling self-powered DBS in mice. This device adopts an indium modified crystalline Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 (PIMNT) thin film on a plastic substrate to transform tiny mechanical motions to electricity. With slight bending, it generates an extremely high current reaching 0.57 mA, which satisfies the high threshold current for real-time DBS of the motor cortex and thereby could efficiently induce forearm movements in mice. The PIMNT based flexible energy harvester could open a new avenue for future in vivo healthcare technology using self-powered biomedical devices.",
author = "Hwang, {Geon Tae} and Youngsoo Kim and Lee, {Jeong Ho} and Sekwon Oh and Jeong, {Chang Kyu} and Park, {Dae Yong} and Jungho Ryu and Hyuksang Kwon and Lee, {Sang Goo} and Boyoung Joung and Daesoo Kim and Lee, {Keon Jae}",
year = "2015",
month = "9",
day = "1",
doi = "10.1039/c5ee01593f",
language = "English",
volume = "8",
pages = "2677--2684",
journal = "Energy and Environmental Science",
issn = "1754-5692",
publisher = "Royal Society of Chemistry",
number = "9",

}

Hwang, GT, Kim, Y, Lee, JH, Oh, S, Jeong, CK, Park, DY, Ryu, J, Kwon, H, Lee, SG, Joung, B, Kim, D & Lee, KJ 2015, 'Self-powered deep brain stimulation via a flexible PIMNT energy harvester', Energy and Environmental Science, vol. 8, no. 9, pp. 2677-2684. https://doi.org/10.1039/c5ee01593f

Self-powered deep brain stimulation via a flexible PIMNT energy harvester. / Hwang, Geon Tae; Kim, Youngsoo; Lee, Jeong Ho; Oh, Sekwon; Jeong, Chang Kyu; Park, Dae Yong; Ryu, Jungho; Kwon, Hyuksang; Lee, Sang Goo; Joung, Boyoung; Kim, Daesoo; Lee, Keon Jae.

In: Energy and Environmental Science, Vol. 8, No. 9, 01.09.2015, p. 2677-2684.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Self-powered deep brain stimulation via a flexible PIMNT energy harvester

AU - Hwang, Geon Tae

AU - Kim, Youngsoo

AU - Lee, Jeong Ho

AU - Oh, Sekwon

AU - Jeong, Chang Kyu

AU - Park, Dae Yong

AU - Ryu, Jungho

AU - Kwon, Hyuksang

AU - Lee, Sang Goo

AU - Joung, Boyoung

AU - Kim, Daesoo

AU - Lee, Keon Jae

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Deep brain stimulation (DBS) is widely used for neural prosthetics and brain-computer interfacing. Thus far in vivo implantation of a battery has been a prerequisite to supply the necessary power. Although flexible energy harvesters have recently emerged as alternatives to batteries, they generate insufficient energy for operating brain stimulation. Herein, we report a high performance flexible piezoelectric energy harvester by enabling self-powered DBS in mice. This device adopts an indium modified crystalline Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 (PIMNT) thin film on a plastic substrate to transform tiny mechanical motions to electricity. With slight bending, it generates an extremely high current reaching 0.57 mA, which satisfies the high threshold current for real-time DBS of the motor cortex and thereby could efficiently induce forearm movements in mice. The PIMNT based flexible energy harvester could open a new avenue for future in vivo healthcare technology using self-powered biomedical devices.

AB - Deep brain stimulation (DBS) is widely used for neural prosthetics and brain-computer interfacing. Thus far in vivo implantation of a battery has been a prerequisite to supply the necessary power. Although flexible energy harvesters have recently emerged as alternatives to batteries, they generate insufficient energy for operating brain stimulation. Herein, we report a high performance flexible piezoelectric energy harvester by enabling self-powered DBS in mice. This device adopts an indium modified crystalline Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 (PIMNT) thin film on a plastic substrate to transform tiny mechanical motions to electricity. With slight bending, it generates an extremely high current reaching 0.57 mA, which satisfies the high threshold current for real-time DBS of the motor cortex and thereby could efficiently induce forearm movements in mice. The PIMNT based flexible energy harvester could open a new avenue for future in vivo healthcare technology using self-powered biomedical devices.

UR - http://www.scopus.com/inward/record.url?scp=84940476219&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940476219&partnerID=8YFLogxK

U2 - 10.1039/c5ee01593f

DO - 10.1039/c5ee01593f

M3 - Article

AN - SCOPUS:84940476219

VL - 8

SP - 2677

EP - 2684

JO - Energy and Environmental Science

JF - Energy and Environmental Science

SN - 1754-5692

IS - 9

ER -