Sensing the environment: Lessons from fungi

Yong Sun Bahn, Chaoyang Xue, Alexander Idnurm, Julian C. Rutherford, Joseph Heitman, Maria E. Cardenas

Research output: Contribution to journalReview article

217 Citations (Scopus)

Abstract

All living organisms use numerous signal-transduction systems to sense and respond to their environments and thereby survive and proliferate in a range of biological niches. Molecular dissection of these signalling networks has increased our understanding of these communication processes and provides a platform for therapeutic intervention when these pathways malfunction in disease states, including infection. Owing to the expanding availability of sequenced genomes, a wealth of genetic and molecular tools and the conservation of signalling networks, members of the fungal kingdom serve as excellent model systems for more complex, multicellular organisms. Here, we review recent progress in our understanding of how fungal-signalling circuits operate at the molecular level to sense and respond to a plethora of environmental cues.

Original languageEnglish
Pages (from-to)57-69
Number of pages13
JournalNature Reviews Microbiology
Volume5
Issue number1
DOIs
Publication statusPublished - 2007 Jan 1

Fingerprint

Cues
Dissection
Molecular Biology
Signal Transduction
Fungi
Communication
Genome
Infection
Therapeutics

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology and Microbiology(all)
  • Infectious Diseases

Cite this

Bahn, Y. S., Xue, C., Idnurm, A., Rutherford, J. C., Heitman, J., & Cardenas, M. E. (2007). Sensing the environment: Lessons from fungi. Nature Reviews Microbiology, 5(1), 57-69. https://doi.org/10.1038/nrmicro1578
Bahn, Yong Sun ; Xue, Chaoyang ; Idnurm, Alexander ; Rutherford, Julian C. ; Heitman, Joseph ; Cardenas, Maria E. / Sensing the environment : Lessons from fungi. In: Nature Reviews Microbiology. 2007 ; Vol. 5, No. 1. pp. 57-69.
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Bahn, YS, Xue, C, Idnurm, A, Rutherford, JC, Heitman, J & Cardenas, ME 2007, 'Sensing the environment: Lessons from fungi', Nature Reviews Microbiology, vol. 5, no. 1, pp. 57-69. https://doi.org/10.1038/nrmicro1578

Sensing the environment : Lessons from fungi. / Bahn, Yong Sun; Xue, Chaoyang; Idnurm, Alexander; Rutherford, Julian C.; Heitman, Joseph; Cardenas, Maria E.

In: Nature Reviews Microbiology, Vol. 5, No. 1, 01.01.2007, p. 57-69.

Research output: Contribution to journalReview article

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Bahn YS, Xue C, Idnurm A, Rutherford JC, Heitman J, Cardenas ME. Sensing the environment: Lessons from fungi. Nature Reviews Microbiology. 2007 Jan 1;5(1):57-69. https://doi.org/10.1038/nrmicro1578