Seroprevalence of tuberculosis in domesticated elk (Cervus canadensis) in Korea

Shin Seok Kang, Hyeon Seop Byeon, Bok Kyung Ku, Sang Woo Kim, Jiro Kim, Jeongim Woo, Byeongwoo Ahn, Soojin Kim, Sezim Monoldorova, Chan Ho Park, Sang Nae Cho, Bo Young Jeon

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4 Citations (Scopus)


Tuberculosis is a contagious disease in animals, primarily cattle, although it also affects wild animals and humans. There are few data on the state of tuberculosis in domesticated elk (Cervus canadensis) in Korea. In order to investigate tuberculosis in elk, the effectiveness of an enzyme linked immunosorbent assay (ELISA) using MPB70 and MPB83 antigens was compared with the tuberculin skin test (TST), and seroprevalence was measured with this assay using serum samples collected from domesticated elk herds in Korea. The respective sensitivities of the MPB70 and MPB83 ELISAs were 51.9% (95% CI 42.0-61.6) and 49.1% (95% CI 39.3-58.9), and their specificities were 100.0% (95% CI 92.6-100.0) and 97.9% (95% CI 88.9-100.0), respectively, in comparison with the TST. The herd prevalence ranged from 50 to 80% and the mean herd seropositive rate was 67.7% (21 of 31). Of 819 serum samples, 163 (19.9%) were seropositive, and the within-region prevalence ranged from 18.5-58.0%. In conclusion, the ELISA using the MPB70 and MPB83 antigens showed moderate sensitivity and high specificity compared to TST in elk, and tuberculosis was assumed to be fairly prevalent in domesticated elk in Korea.

Original languageEnglish
Pages (from-to)228-232
Number of pages5
JournalResearch in Veterinary Science
Publication statusPublished - 2016 Aug 1

Bibliographical note

Funding Information:
This research was supported by a grant from the Bio-industry Technology Development Programme , the Ministry of Agriculture, Food and Rural Affairs, Korea (grant no. 314025-03 ), by a grant from the Animal and Plant Quarantine Agency, Korea ( Z -AD13-2010-11-0502 ), and in part by the Yonsei University Research Fund of 2015 .

Publisher Copyright:
© 2016 Elsevier Ltd.

All Science Journal Classification (ASJC) codes

  • veterinary(all)


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