Bibliographical noteFunding Information:
The authors acknowledge Simon Yarrow for conducting anaesthesia on some of the patients, and Peter Brown for constructive and critical comments. The scheme is generously supported by the Wellcome Trust , Medical Research Council , British Heart Foundation , Versus Arthritis , Diabetes UK , and British Thoracic Society (through the Helen and Andrew Douglas bequest). The views expressed are those of the authors and not necessarily those of the National Institute for Health Research, National Health Service, or the Department of Health and Social Care.
Shanghai Pujiang Program ( 19PJ1407500 ) to KH; Medical and Engineering Cross Research Fund from Shanghai Jiao Tong University ( YG2019QNA31 ) to KH; Shanghai Municipal Health Commission Clinical Study Special Fund ( 20194Y0067 ) to KH; Ruijin Hospital Guangci Excellence Youth Training Program ( GCQN-2019-B10 ) to KH; Ruijin Youth Natural Science Foundation of China Cultivation Fund ( 2019QNPY01031 ) to KH; National Institute for Health Research Oxford Biomedical Research Centre to YH ; Shanghai Municipal Science and Technology Major Project ( 2018SHZDZX01 ) and ZJLab to SW; National Natural Science Foundation of China ( 81471482 ) to BS; Shanghai Jiao Tong University School of Medicine –Institute of Neuroscience Research Center for Brain Disorders to BS; Academy of Medical Sciences , Starter Grant for Clinical lecturers to MJG; National Institute for Health Research Academy (Ref. CL-2013-13-001 ) to MJG.
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