Abstract
We investigated the adjunctive role of preoperative serum thyroglobulin (Tg) in the diagnosis of thyroid nodules. A retrospective study was performed on 374 thyroid nodules (363 benign and 11 malignant) in 360 patients (296 women and 64 men;mean age, 50.1 years; range, 16-86 years) between December 2010 and July 2011. We evaluated clinicopathologic characteristics of patients and ultrasonographic (US) features of the lesions including presurgical Tg levels. Univariate and multivariate analysis were used to determine independent predictors of malignancy. SerumTgwas positively correlatedwith nodule size and thyroid volume (P < 0.001). There was no difference in serum Tg levels between malignant and benign nodules. Suspicious US features of thyroid nodules were the only independent predictors of malignancy (P< 0.001). Preoperative serum Tg was not useful in differentiating thyroid cancer from benign nodules. Suspicious US features were the only predicting factors for malignancy.
| Original language | English |
|---|---|
| Pages (from-to) | 287-290 |
| Number of pages | 4 |
| Journal | Ultrasound Quarterly |
| Volume | 30 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2014 Dec 11 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
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Serum thyroglobulin adds no additional value to ultrasonographic features in a thyroid malignancy. / Youn, Inyoung; Sung, Ji Min; Kim, Eunkyung; kwak, jinyoung.
In: Ultrasound Quarterly, Vol. 30, No. 4, 11.12.2014, p. 287-290.Research output: Contribution to journal › Article
TY - JOUR
T1 - Serum thyroglobulin adds no additional value to ultrasonographic features in a thyroid malignancy
AU - Youn, Inyoung
AU - Sung, Ji Min
AU - Kim, Eunkyung
AU - kwak, jinyoung
PY - 2014/12/11
Y1 - 2014/12/11
N2 - We investigated the adjunctive role of preoperative serum thyroglobulin (Tg) in the diagnosis of thyroid nodules. A retrospective study was performed on 374 thyroid nodules (363 benign and 11 malignant) in 360 patients (296 women and 64 men;mean age, 50.1 years; range, 16-86 years) between December 2010 and July 2011. We evaluated clinicopathologic characteristics of patients and ultrasonographic (US) features of the lesions including presurgical Tg levels. Univariate and multivariate analysis were used to determine independent predictors of malignancy. SerumTgwas positively correlatedwith nodule size and thyroid volume (P < 0.001). There was no difference in serum Tg levels between malignant and benign nodules. Suspicious US features of thyroid nodules were the only independent predictors of malignancy (P< 0.001). Preoperative serum Tg was not useful in differentiating thyroid cancer from benign nodules. Suspicious US features were the only predicting factors for malignancy.
AB - We investigated the adjunctive role of preoperative serum thyroglobulin (Tg) in the diagnosis of thyroid nodules. A retrospective study was performed on 374 thyroid nodules (363 benign and 11 malignant) in 360 patients (296 women and 64 men;mean age, 50.1 years; range, 16-86 years) between December 2010 and July 2011. We evaluated clinicopathologic characteristics of patients and ultrasonographic (US) features of the lesions including presurgical Tg levels. Univariate and multivariate analysis were used to determine independent predictors of malignancy. SerumTgwas positively correlatedwith nodule size and thyroid volume (P < 0.001). There was no difference in serum Tg levels between malignant and benign nodules. Suspicious US features of thyroid nodules were the only independent predictors of malignancy (P< 0.001). Preoperative serum Tg was not useful in differentiating thyroid cancer from benign nodules. Suspicious US features were the only predicting factors for malignancy.
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UR - http://www.scopus.com/inward/citedby.url?scp=84917734961&partnerID=8YFLogxK
U2 - 10.1097/RUQ.0000000000000056
DO - 10.1097/RUQ.0000000000000056
M3 - Article
C2 - 25415866
AN - SCOPUS:84917734961
VL - 30
SP - 287
EP - 290
JO - Ultrasound Quarterly
JF - Ultrasound Quarterly
SN - 0894-8771
IS - 4
ER -