Abstract
Investigation of antiinflammatory constituents of the stem and root barks of Ulmus davidiana var. japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.
| Original language | English |
|---|---|
| Pages (from-to) | 196-199 |
| Number of pages | 4 |
| Journal | Fitoterapia |
| Volume | 78 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2007 Apr 1 |
All Science Journal Classification (ASJC) codes
- Pharmacology
- Drug Discovery
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Kim, Y. C., Lee, M. K., Sung, S. H., & Kim, S. H. (2007). Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production. Fitoterapia, 78(3), 196-199. https://doi.org/10.1016/j.fitote.2006.11.013