Abstract
Investigation of antiinflammatory constituents of the stem and root barks of Ulmus davidiana var. japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.
Original language | English |
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Pages (from-to) | 196-199 |
Number of pages | 4 |
Journal | Fitoterapia |
Volume | 78 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2007 Apr |
Bibliographical note
Funding Information:This research was supported by the Korea Research Foundation Grant (KRF-2003-015-E00216).
All Science Journal Classification (ASJC) codes
- Pharmacology
- Drug Discovery