Abstract
Investigation of antiinflammatory constituents of the stem and root barks of Ulmus davidiana var. japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.
| Original language | English |
|---|---|
| Pages (from-to) | 196-199 |
| Number of pages | 4 |
| Journal | Fitoterapia |
| Volume | 78 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2007 Apr 1 |
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All Science Journal Classification (ASJC) codes
- Pharmacology
- Drug Discovery
Cite this
}
Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production. / Kim, Young Choong; Lee, Mi Kyeong; Sung, Sang Hyun; Kim, Seung Hyun.
In: Fitoterapia, Vol. 78, No. 3, 01.04.2007, p. 196-199.Research output: Contribution to journal › Article
TY - JOUR
T1 - Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production
AU - Kim, Young Choong
AU - Lee, Mi Kyeong
AU - Sung, Sang Hyun
AU - Kim, Seung Hyun
PY - 2007/4/1
Y1 - 2007/4/1
N2 - Investigation of antiinflammatory constituents of the stem and root barks of Ulmus davidiana var. japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.
AB - Investigation of antiinflammatory constituents of the stem and root barks of Ulmus davidiana var. japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.
UR - http://www.scopus.com/inward/record.url?scp=34047268560&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34047268560&partnerID=8YFLogxK
U2 - 10.1016/j.fitote.2006.11.013
DO - 10.1016/j.fitote.2006.11.013
M3 - Article
C2 - 17343992
AN - SCOPUS:34047268560
VL - 78
SP - 196
EP - 199
JO - Fitoterapia
JF - Fitoterapia
SN - 0367-326X
IS - 3
ER -