Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production

Young Choong Kim, Mi Kyeong Lee, Sang Hyun Sung, Seung Hyun Kim

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Investigation of antiinflammatory constituents of the stem and root barks of Ulmus davidiana var. japonica resulted in the isolation of three guaiane type sesquiterpenes, torilin, 1-hydroxytorilin, together with a new derivative, (1β, 7β, 8β, 10β)-1,8,11-trihydroxy-4-guaien-8-angeloyl-3-one named 1-hydroxytorilin A. All the three sesquiterpenes inhibited lipopolysaccharide-induced nitric oxide production in murine microglial BV2 cells.

Original languageEnglish
Pages (from-to)196-199
Number of pages4
JournalFitoterapia
Volume78
Issue number3
DOIs
Publication statusPublished - 2007 Apr 1

Fingerprint

Guaiane Sesquiterpenes
Ulmus
Sesquiterpenes
Lipopolysaccharides
Nitric Oxide
Anti-Inflammatory Agents
torilin

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

Cite this

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Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production. / Kim, Young Choong; Lee, Mi Kyeong; Sung, Sang Hyun; Kim, Seung Hyun.

In: Fitoterapia, Vol. 78, No. 3, 01.04.2007, p. 196-199.

Research output: Contribution to journalArticle

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