Severe acute stent malapposition follow-up: 3-month and 12-month serial quantitative analyses by optical coherence tomography

Sung Jin Hong, Keun Hee Park, Chul Min Ahn, Jung Sun Kim, Byeong Keuk Kim, Young Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong Ki Hong

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Optical coherence tomography (OCT) was used to assess serial changes in severe acute stent malapposition (ASM) after drug-eluting stent (DES) implantation. Methods: The maximal depth and axial lengths of ASM after DES implantation were serially quantified at percutaneous coronary intervention (PCI), and at 3 and 12-month follow-up, for 100 lesions in 96 patients. Severe ASM was defined as a maximal malapposed depth ≥400 μm or maximal malapposed axial length ≥1 mm. Results: Of the 100 lesions, 23 lesions (23%) had a severe ASM depth at PCI. At 3 months, the maximal depth decreased to <400 μm in 12 of 23 lesions (52%). At 12 months, the maximal depth further decreased to <400 μm in 8 of the remaining 11 lesions (73%). Similarly, of 53 lesions (53%) with a severe ASM length at PCI, the maximal length decreased to 0 mm in 26 (49%) but remained severe in 17 lesions (32%) at 3 months. At 12 months, 9 of the 17 remaining lesions (53%) further decreased to 0 mm. The cut-off values for the maximal malapposed depth and length to predict the absence of stent malapposition at 12 months were 565 μm at PCI and 165 μm at 3 months, and were 2.7 mm at PCI and 0.1 mm at 3 months, respectively. Conclusion: Half of the severe ASM cases resolved within 3 months, and another half resolved during 3–12 months of follow-up. Our findings provide a better understanding of the time-dependent natural course of severe ASM using OCT.

Original languageEnglish
Pages (from-to)81-86
Number of pages6
JournalInternational Journal of Cardiology
Volume299
DOIs
Publication statusPublished - 2020 Jan 15

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Optical Coherence Tomography
Stents
Percutaneous Coronary Intervention
Drug-Eluting Stents

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Severe acute stent malapposition follow-up: 3-month and 12-month serial quantitative analyses by optical coherence tomography",
abstract = "Background: Optical coherence tomography (OCT) was used to assess serial changes in severe acute stent malapposition (ASM) after drug-eluting stent (DES) implantation. Methods: The maximal depth and axial lengths of ASM after DES implantation were serially quantified at percutaneous coronary intervention (PCI), and at 3 and 12-month follow-up, for 100 lesions in 96 patients. Severe ASM was defined as a maximal malapposed depth ≥400 μm or maximal malapposed axial length ≥1 mm. Results: Of the 100 lesions, 23 lesions (23{\%}) had a severe ASM depth at PCI. At 3 months, the maximal depth decreased to <400 μm in 12 of 23 lesions (52{\%}). At 12 months, the maximal depth further decreased to <400 μm in 8 of the remaining 11 lesions (73{\%}). Similarly, of 53 lesions (53{\%}) with a severe ASM length at PCI, the maximal length decreased to 0 mm in 26 (49{\%}) but remained severe in 17 lesions (32{\%}) at 3 months. At 12 months, 9 of the 17 remaining lesions (53{\%}) further decreased to 0 mm. The cut-off values for the maximal malapposed depth and length to predict the absence of stent malapposition at 12 months were 565 μm at PCI and 165 μm at 3 months, and were 2.7 mm at PCI and 0.1 mm at 3 months, respectively. Conclusion: Half of the severe ASM cases resolved within 3 months, and another half resolved during 3–12 months of follow-up. Our findings provide a better understanding of the time-dependent natural course of severe ASM using OCT.",
author = "Hong, {Sung Jin} and Park, {Keun Hee} and Ahn, {Chul Min} and Kim, {Jung Sun} and Kim, {Byeong Keuk} and Ko, {Young Guk} and Donghoon Choi and Yangsoo Jang and Hong, {Myeong Ki}",
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Severe acute stent malapposition follow-up : 3-month and 12-month serial quantitative analyses by optical coherence tomography. / Hong, Sung Jin; Park, Keun Hee; Ahn, Chul Min; Kim, Jung Sun; Kim, Byeong Keuk; Ko, Young Guk; Choi, Donghoon; Jang, Yangsoo; Hong, Myeong Ki.

In: International Journal of Cardiology, Vol. 299, 15.01.2020, p. 81-86.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Severe acute stent malapposition follow-up

T2 - 3-month and 12-month serial quantitative analyses by optical coherence tomography

AU - Hong, Sung Jin

AU - Park, Keun Hee

AU - Ahn, Chul Min

AU - Kim, Jung Sun

AU - Kim, Byeong Keuk

AU - Ko, Young Guk

AU - Choi, Donghoon

AU - Jang, Yangsoo

AU - Hong, Myeong Ki

PY - 2020/1/15

Y1 - 2020/1/15

N2 - Background: Optical coherence tomography (OCT) was used to assess serial changes in severe acute stent malapposition (ASM) after drug-eluting stent (DES) implantation. Methods: The maximal depth and axial lengths of ASM after DES implantation were serially quantified at percutaneous coronary intervention (PCI), and at 3 and 12-month follow-up, for 100 lesions in 96 patients. Severe ASM was defined as a maximal malapposed depth ≥400 μm or maximal malapposed axial length ≥1 mm. Results: Of the 100 lesions, 23 lesions (23%) had a severe ASM depth at PCI. At 3 months, the maximal depth decreased to <400 μm in 12 of 23 lesions (52%). At 12 months, the maximal depth further decreased to <400 μm in 8 of the remaining 11 lesions (73%). Similarly, of 53 lesions (53%) with a severe ASM length at PCI, the maximal length decreased to 0 mm in 26 (49%) but remained severe in 17 lesions (32%) at 3 months. At 12 months, 9 of the 17 remaining lesions (53%) further decreased to 0 mm. The cut-off values for the maximal malapposed depth and length to predict the absence of stent malapposition at 12 months were 565 μm at PCI and 165 μm at 3 months, and were 2.7 mm at PCI and 0.1 mm at 3 months, respectively. Conclusion: Half of the severe ASM cases resolved within 3 months, and another half resolved during 3–12 months of follow-up. Our findings provide a better understanding of the time-dependent natural course of severe ASM using OCT.

AB - Background: Optical coherence tomography (OCT) was used to assess serial changes in severe acute stent malapposition (ASM) after drug-eluting stent (DES) implantation. Methods: The maximal depth and axial lengths of ASM after DES implantation were serially quantified at percutaneous coronary intervention (PCI), and at 3 and 12-month follow-up, for 100 lesions in 96 patients. Severe ASM was defined as a maximal malapposed depth ≥400 μm or maximal malapposed axial length ≥1 mm. Results: Of the 100 lesions, 23 lesions (23%) had a severe ASM depth at PCI. At 3 months, the maximal depth decreased to <400 μm in 12 of 23 lesions (52%). At 12 months, the maximal depth further decreased to <400 μm in 8 of the remaining 11 lesions (73%). Similarly, of 53 lesions (53%) with a severe ASM length at PCI, the maximal length decreased to 0 mm in 26 (49%) but remained severe in 17 lesions (32%) at 3 months. At 12 months, 9 of the 17 remaining lesions (53%) further decreased to 0 mm. The cut-off values for the maximal malapposed depth and length to predict the absence of stent malapposition at 12 months were 565 μm at PCI and 165 μm at 3 months, and were 2.7 mm at PCI and 0.1 mm at 3 months, respectively. Conclusion: Half of the severe ASM cases resolved within 3 months, and another half resolved during 3–12 months of follow-up. Our findings provide a better understanding of the time-dependent natural course of severe ASM using OCT.

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DO - 10.1016/j.ijcard.2019.06.075

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JO - International Journal of Cardiology

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