Shape deformation of the insula in alcoholics: Reduction of left-right asymmetry

Young Chul Jung, Dong Pyo Jang, Kee Namkoong, Jeonghun Ku, Jae Jin Kim, Sangjin Park, Zang Hee Cho, Young Bo Kim, Eun Lee

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


We have investigated shape deformation of the insula to get a viewpoint of how chronic alcohol consumption affects the perisylvian region and compared the deformity pattern between the left and right hemisphere. A landmark-based structural and surface shape analysis of the insula was performed in 20 patients with alcohol dependence and 20 controls matched for age. The shape analysis revealed that the left and right insula follow distinct shape deformation patterns, which resulted in the reduction of left-right asymmetry. The shape deformity was most prominent in the central part of both insula. Our findings indicate that the right and left hemisphere are both affected but shows distinct patterns of deformation in alcohol dependence.

Original languageEnglish
Pages (from-to)1787-1791
Number of pages5
Issue number17
Publication statusPublished - 2007 Nov

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)


Dive into the research topics of 'Shape deformation of the insula in alcoholics: Reduction of left-right asymmetry'. Together they form a unique fingerprint.

Cite this