Silicon-based thiourea-mediated and microwave-assisted thio-Michael addition under solvent-free reaction conditions

Kamalakannan Prabakaran, MacHindra Gund, Tae Kyu Kim, Euh Duck Jeong, Chae Young Oh, Fazlur Rahman Nawaz Khan, Jong Sung Jin

Research output: Contribution to journalArticle

2 Citations (Scopus)


Silicon-based thiourea (SiliaBond® Thiourea) (Si-THU), a heterogeneous catalyst, has been applied to the highly selective C\-S bond formation via Michael addition of thiols to a,β-unsaturated carbonyl compounds under solvent-free conditions at 55-60°C. The thio-Michael addition products were obtained in an excellent yield under optimised conditions. This methodology involving a metal-free as well as a metal scavenger catalyst has been found to be an alternative method for the thio-Michael addition reaction.

Original languageEnglish
Pages (from-to)707-713
Number of pages7
JournalChemical Papers
Issue number5
Publication statusPublished - 2011 Oct 1


All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Biochemistry
  • Chemical Engineering(all)
  • Industrial and Manufacturing Engineering
  • Materials Chemistry

Cite this