Silver-mediated direct amination of benzoxazoles: Tuning the amino group source from formamides to parent amines

Seung Hwan Cho, Ji Young Kim, S. Yunmi Lee, Sukbok Chang

Research output: Contribution to journalArticlepeer-review

262 Citations (Scopus)

Abstract

Formamides or parent amines were used as an amino group source for the silver-mediated amination of benzoxazoles. Although reactions with formamides proceeded at high temperatures, the direct amination with amines took place under much milder conditions (see scheme). Optically active amino groups could also be installed without racemization.

Original languageEnglish
Pages (from-to)9127-9130
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number48
DOIs
Publication statusPublished - 2009 Nov 16

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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