Single-, few-, and multilayer graphene not exhibiting significant advantages over graphite microparticles in electroanalysis

Madeline Shuhua Goh, Martin Pumera

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66 Citations (Scopus)


This report compares the electroanalytical performances of single- (G-SL), few- (G-FL), and multilayer graphene (G-ML), graphite microparticles, and edge-plane pyrolytic graphite electrodes in terms of sensitivity, linearity, and repeatability. We show that in the case of differential pulse voltammetric (DPV) detection of ascorbic acid, the sensitivity of a G-SL electrode is about 30% greater than that of G-ML and about 40% greater than graphite microparticles. However, in the case of DPV determination of uric acid, sensitivity is practically the same for all (G-SL, G-FL, and G-ML) and, importantly, the graphite microparticles do provide higher sensitivity than graphenes do for this analyte. Graphenes also do not provide a significant advantage in terms of repeatability. We pose the question of whether the efforts leading to the bulk method of producing single-layer graphene are justified for electroanalytical applications.

Original languageEnglish
Pages (from-to)8367-8370
Number of pages4
JournalAnalytical Chemistry
Issue number19
Publication statusPublished - 2010 Oct 1


All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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