Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis

Hak Lee Sang, Young Guk Ko, Yangsoo Jang, Moon Kwon Hyuck, Seung Hwan Lee, Jung Han Yoon, Hoon Park Si, Ok Kim Byung, Woon Jeon Dong, Young Yang Joo, Seung Ki Ryu

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Abstract

We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.

Original languageEnglish
Pages (from-to)181-185
Number of pages5
JournalCardiology
Volume104
Issue number4
DOIs
Publication statusPublished - 2005 Sep 1

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Coronary Stenosis
Sirolimus
Paclitaxel
Stents
Coronary Vessels

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

Cite this

Sang, Hak Lee ; Ko, Young Guk ; Jang, Yangsoo ; Hyuck, Moon Kwon ; Lee, Seung Hwan ; Yoon, Jung Han ; Si, Hoon Park ; Byung, Ok Kim ; Dong, Woon Jeon ; Joo, Young Yang ; Ryu, Seung Ki. / Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis. In: Cardiology. 2005 ; Vol. 104, No. 4. pp. 181-185.
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Sang, HL, Ko, YG, Jang, Y, Hyuck, MK, Lee, SH, Yoon, JH, Si, HP, Byung, OK, Dong, WJ, Joo, YY & Ryu, SK 2005, 'Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis', Cardiology, vol. 104, no. 4, pp. 181-185. https://doi.org/10.1159/000088106

Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis. / Sang, Hak Lee; Ko, Young Guk; Jang, Yangsoo; Hyuck, Moon Kwon; Lee, Seung Hwan; Yoon, Jung Han; Si, Hoon Park; Byung, Ok Kim; Dong, Woon Jeon; Joo, Young Yang; Ryu, Seung Ki.

In: Cardiology, Vol. 104, No. 4, 01.09.2005, p. 181-185.

Research output: Contribution to journalArticle

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AU - Sang, Hak Lee

AU - Ko, Young Guk

AU - Jang, Yangsoo

AU - Hyuck, Moon Kwon

AU - Lee, Seung Hwan

AU - Yoon, Jung Han

AU - Si, Hoon Park

AU - Byung, Ok Kim

AU - Dong, Woon Jeon

AU - Joo, Young Yang

AU - Ryu, Seung Ki

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N2 - We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.

AB - We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.

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