Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis

Hak Lee Sang, Young Guk Ko, Yangsoo Jang, Moon Kwon Hyuck, Seung Hwan Lee, Jung Han Yoon, Hoon Park Si, Ok Kim Byung, Woon Jeon Dong, Young Yang Joo, Seung Ki Ryu

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Abstract

We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.

Original languageEnglish
Pages (from-to)181-185
Number of pages5
JournalCardiology
Volume104
Issue number4
DOIs
Publication statusPublished - 2005 Sep 1

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

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    Sang, H. L., Ko, Y. G., Jang, Y., Hyuck, M. K., Lee, S. H., Yoon, J. H., Si, H. P., Byung, O. K., Dong, W. J., Joo, Y. Y., & Ryu, S. K. (2005). Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis. Cardiology, 104(4), 181-185. https://doi.org/10.1159/000088106