Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis

Hak Lee Sang; Young Guk Ko; Yangsoo Jang; Moon Kwon Hyuck; Seung Hwan Lee; Jung Han Yoon; Hoon Park Si; Ok Kim Byung; Woon Jeon Dong; Young Yang Joo; Seung Ki Ryu

doi:10.1159/000088106

Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis

Hak Lee Sang, Young Guk Ko, Yangsoo Jang, Moon Kwon Hyuck, Seung Hwan Lee, Jung Han Yoon, Hoon Park Si, Ok Kim Byung, Woon Jeon Dong, Young Yang Joo, Seung Ki Ryu

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37 Citations (Scopus)

Abstract

We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.

Original language	English
Pages (from-to)	181-185
Number of pages	5
Journal	Cardiology
Volume	104
Issue number	4
DOIs	https://doi.org/10.1159/000088106
Publication status	Published - 2005 Sept

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine
Pharmacology (medical)

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10.1159/000088106

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title = "Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis",

abstract = "We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.",

author = "Sang, {Hak Lee} and Ko, {Young Guk} and Yangsoo Jang and Hyuck, {Moon Kwon} and Lee, {Seung Hwan} and Yoon, {Jung Han} and Si, {Hoon Park} and Byung, {Ok Kim} and Dong, {Woon Jeon} and Joo, {Young Yang} and Ryu, {Seung Ki}",

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doi = "10.1159/000088106",

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T1 - Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis

AU - Sang, Hak Lee

AU - Ko, Young Guk

AU - Jang, Yangsoo

AU - Hyuck, Moon Kwon

AU - Lee, Seung Hwan

AU - Yoon, Jung Han

AU - Si, Hoon Park

AU - Byung, Ok Kim

AU - Dong, Woon Jeon

AU - Joo, Young Yang

AU - Ryu, Seung Ki

PY - 2005/9

Y1 - 2005/9

N2 - We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.

AB - We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES group, and 88% in the PES group (p = 0.07). At the 6-month angiographic follow-up (n = 24), the SES group exhibited a slightly lower late loss than did the PES group (0.24 ± 0.44 vs. 0.65 ± 0.60 mm, p = 0.09), and the restenosis rates were 8 and 9% (p = 0.94) in the SES and PES patients, respectively. In conclusion, both groups exhibited excellent in-hospital and 6-month outcomes with no significant differences between them.

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Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis

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