Skeletal muscle dressed in SOCs

Dong Min Shin, Shmuel Muallem

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Store-operated Ca2+ channels (SOCs) are activated in response to Ca2+ release from the endoplasmic reticulum (ER). The stromal interaction molecule 1 (STIM1) is the ER sensor that transmits the stored Ca2+ content to the pore-forming SOCs Orai and TRPC channels. Recent studies reveal high levels of Orai1 and STIM1 in skeletal muscle, and a prominent role of SOCs in muscle development and function.

Original languageEnglish
Pages (from-to)639-641
Number of pages3
JournalNature Cell Biology
Volume10
Issue number6
DOIs
Publication statusPublished - 2008 Jun 1

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All Science Journal Classification (ASJC) codes

  • Cell Biology

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