Skeletal Reorganization: Synthesis of Diptoindonesin G from Pauciflorol F

Dileep Kumar Singh; Ikyon Kim

doi:10.1021/acs.joc.7b03089

Skeletal Reorganization: Synthesis of Diptoindonesin G from Pauciflorol F

Dileep Kumar Singh, Ikyon Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Described herein is a novel synthetic approach to diptoindonesin G, a highly potent anticancer oligostilbenoid natural product, from pauciflorol F pentamethyl ether through a skeletal reorganization strategy where oxidative cleavage of the indanone ring system of pauciflorol F and sequential cyclization of the key intermediate allowed direct access to the target skeleton.

Original language	English
Pages (from-to)	1667-1672
Number of pages	6
Journal	Journal of Organic Chemistry
Volume	83
Issue number	3
DOIs	https://doi.org/10.1021/acs.joc.7b03089
Publication status	Published - 2018 Feb 2

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (2017R1A2A2A05069364).

Publisher Copyright:
© 2018 American Chemical Society.

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1021/acs.joc.7b03089

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abstract = "Described herein is a novel synthetic approach to diptoindonesin G, a highly potent anticancer oligostilbenoid natural product, from pauciflorol F pentamethyl ether through a skeletal reorganization strategy where oxidative cleavage of the indanone ring system of pauciflorol F and sequential cyclization of the key intermediate allowed direct access to the target skeleton.",

author = "Singh, {Dileep Kumar} and Ikyon Kim",

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AB - Described herein is a novel synthetic approach to diptoindonesin G, a highly potent anticancer oligostilbenoid natural product, from pauciflorol F pentamethyl ether through a skeletal reorganization strategy where oxidative cleavage of the indanone ring system of pauciflorol F and sequential cyclization of the key intermediate allowed direct access to the target skeleton.

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Skeletal Reorganization: Synthesis of Diptoindonesin G from Pauciflorol F

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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