Smoking cessation and risk of type 2 diabetes mellitus: Korea Medical Insurance Corporation Study

Nam Wook Hur, HyeonChang Kim, Chung mo Nam, Sun ha Jee, Hyun Chul Lee, il Suh

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

To investigate the independent effects of smoking cessation on the risk for developing type 2 diabetes mellitus (DM) in the general population. An 8-year prospective study. This prospective study started with baseline examinations in 1990 and 1992, and continued with follow-up examinations every 2 years up to 1998 and 2000. A total of 27635 nondiabetic men, aged 35–44 years were classified as 5701 nonsmokers, 7477 ex-smokers and 14457 sustained smokers, based on repeated self-reported questionnaires in 1992, 1994 and 1996. Baseline fasting serum glucose level and other risk factors were measured in 1990 and 1992. The outcome was newly developed DM, defined as a fasting glucose level ≥7.0mmol/l in 1998 and 2000 (averaged). Over the 8 years, 1170 men (4.2%) developed DM. When compared with nonsmokers, the fully adjusted risk ratio of ex-smokers and sustained smokers for diabetes was 1.22 [95% confidence interval (CI), 0.96–1.55] and 1.60 (95% CI, 1.29–1.97), respectively. Among the ex-smokers, the risk for diabetes differed according to the quit-smoking period. Compared with nonsmokers, the fully adjusted risk ratio for DM in men who quit smoking before 1992, during 1992–1993 and during 1994–1995 was 0.95 (0.72–1.25), 1.44 (0.96–2.15) and 2.13 (1.51–3.00), respectively, after adjustment for age, baseline fasting serum glucose, weight change, baseline body mass index, family history of DM, alcohol consumption and exercise status. Our results support cigarette smoking as an independent and modifiable risk factor for DM. Early smoking cessation could decrease the risk for developing DM to that of nonsmokers in the long term.

Original languageEnglish
Pages (from-to)244-249
Number of pages6
JournalEuropean Journal of Preventive Cardiology
Volume14
Issue number2
DOIs
Publication statusPublished - 2007 Jan 1

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Smoking Cessation
Korea
Insurance
Type 2 Diabetes Mellitus
Diabetes Mellitus
Fasting
Smoking
Glucose
Odds Ratio
Prospective Studies
Confidence Intervals
Serum
Alcohol Drinking
Body Mass Index
Exercise
Weights and Measures
Population

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Cardiology and Cardiovascular Medicine

Cite this

Hur, Nam Wook ; Kim, HyeonChang ; mo Nam, Chung ; ha Jee, Sun ; Lee, Hyun Chul ; Suh, il. / Smoking cessation and risk of type 2 diabetes mellitus : Korea Medical Insurance Corporation Study. In: European Journal of Preventive Cardiology. 2007 ; Vol. 14, No. 2. pp. 244-249.
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abstract = "To investigate the independent effects of smoking cessation on the risk for developing type 2 diabetes mellitus (DM) in the general population. An 8-year prospective study. This prospective study started with baseline examinations in 1990 and 1992, and continued with follow-up examinations every 2 years up to 1998 and 2000. A total of 27635 nondiabetic men, aged 35–44 years were classified as 5701 nonsmokers, 7477 ex-smokers and 14457 sustained smokers, based on repeated self-reported questionnaires in 1992, 1994 and 1996. Baseline fasting serum glucose level and other risk factors were measured in 1990 and 1992. The outcome was newly developed DM, defined as a fasting glucose level {\^a}‰¥7.0mmol/l in 1998 and 2000 (averaged). Over the 8 years, 1170 men (4.2{\%}) developed DM. When compared with nonsmokers, the fully adjusted risk ratio of ex-smokers and sustained smokers for diabetes was 1.22 [95{\%} confidence interval (CI), 0.96–1.55] and 1.60 (95{\%} CI, 1.29–1.97), respectively. Among the ex-smokers, the risk for diabetes differed according to the quit-smoking period. Compared with nonsmokers, the fully adjusted risk ratio for DM in men who quit smoking before 1992, during 1992–1993 and during 1994–1995 was 0.95 (0.72–1.25), 1.44 (0.96–2.15) and 2.13 (1.51–3.00), respectively, after adjustment for age, baseline fasting serum glucose, weight change, baseline body mass index, family history of DM, alcohol consumption and exercise status. Our results support cigarette smoking as an independent and modifiable risk factor for DM. Early smoking cessation could decrease the risk for developing DM to that of nonsmokers in the long term.",
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Smoking cessation and risk of type 2 diabetes mellitus : Korea Medical Insurance Corporation Study. / Hur, Nam Wook; Kim, HyeonChang; mo Nam, Chung; ha Jee, Sun; Lee, Hyun Chul; Suh, il.

In: European Journal of Preventive Cardiology, Vol. 14, No. 2, 01.01.2007, p. 244-249.

Research output: Contribution to journalArticle

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