Soft, smart contact lenses with integrations of wireless circuits, glucose sensors, and displays

Jihun Park, Joohee Kim, So Yun Kim, Woon Hyung Cheong, Jiuk Jang, Young Geun Park, Kyungmin Na, Yun Tae Kim, Jun Hyuk Heo, Chang Young Lee, Jung Heon Lee, Franklin Bien, Jang-Ung Park

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Recent advances in wearable electronics combined with wireless communications are essential to the realization of medical applications through health monitoring technologies. For example, a smart contact lens, which is capable of monitoring the physiological information of the eye and tear fluid, could provide real-time, noninvasive medical diagnostics. However, previous reports concerning the smart contact lens have indicated that opaque and brittle components have been used to enable the operation of the electronic device, and this could block the user’s vision and potentially damage the eye. In addition, the use of expensive and bulky equipment to measure signals from the contact lens sensors could interfere with the user’s external activities. Thus, we report an unconventional approach for the fabrication of a soft, smart contact lens in which glucose sensors, wireless power transfer circuits, and display pixels to visualize sensing signals in real time are fully integrated using transparent and stretchable nanostructures. The integration of this display into the smart lens eliminates the need for additional, bulky measurement equipment. This soft, smart contact lens can be transparent, providing a clear view by matching the refractive indices of its locally patterned areas. The resulting soft, smart contact lens provides real-time, wireless operation, and there are in vivo tests to monitor the glucose concentration in tears (suitable for determining the fasting glucose level in the tears of diabetic patients) and, simultaneously, to provide sensing results through the contact lens display.

Original languageEnglish
Article numbereaap9841
JournalScience Advances
Volume4
Issue number1
DOIs
Publication statusPublished - 2018 Jan 1

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Contact lenses
Glucose sensors
Display devices
Networks (circuits)
Glucose
Monitoring
Medical applications
Lenses
Nanostructures
Refractive index
Pixels
Health
Fabrication
Fluids
Communication
Sensors

All Science Journal Classification (ASJC) codes

  • General

Cite this

Park, Jihun ; Kim, Joohee ; Kim, So Yun ; Cheong, Woon Hyung ; Jang, Jiuk ; Park, Young Geun ; Na, Kyungmin ; Kim, Yun Tae ; Heo, Jun Hyuk ; Lee, Chang Young ; Lee, Jung Heon ; Bien, Franklin ; Park, Jang-Ung. / Soft, smart contact lenses with integrations of wireless circuits, glucose sensors, and displays. In: Science Advances. 2018 ; Vol. 4, No. 1.
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abstract = "Recent advances in wearable electronics combined with wireless communications are essential to the realization of medical applications through health monitoring technologies. For example, a smart contact lens, which is capable of monitoring the physiological information of the eye and tear fluid, could provide real-time, noninvasive medical diagnostics. However, previous reports concerning the smart contact lens have indicated that opaque and brittle components have been used to enable the operation of the electronic device, and this could block the user’s vision and potentially damage the eye. In addition, the use of expensive and bulky equipment to measure signals from the contact lens sensors could interfere with the user’s external activities. Thus, we report an unconventional approach for the fabrication of a soft, smart contact lens in which glucose sensors, wireless power transfer circuits, and display pixels to visualize sensing signals in real time are fully integrated using transparent and stretchable nanostructures. The integration of this display into the smart lens eliminates the need for additional, bulky measurement equipment. This soft, smart contact lens can be transparent, providing a clear view by matching the refractive indices of its locally patterned areas. The resulting soft, smart contact lens provides real-time, wireless operation, and there are in vivo tests to monitor the glucose concentration in tears (suitable for determining the fasting glucose level in the tears of diabetic patients) and, simultaneously, to provide sensing results through the contact lens display.",
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Park, J, Kim, J, Kim, SY, Cheong, WH, Jang, J, Park, YG, Na, K, Kim, YT, Heo, JH, Lee, CY, Lee, JH, Bien, F & Park, J-U 2018, 'Soft, smart contact lenses with integrations of wireless circuits, glucose sensors, and displays', Science Advances, vol. 4, no. 1, eaap9841. https://doi.org/10.1126/sciadv.aap9841

Soft, smart contact lenses with integrations of wireless circuits, glucose sensors, and displays. / Park, Jihun; Kim, Joohee; Kim, So Yun; Cheong, Woon Hyung; Jang, Jiuk; Park, Young Geun; Na, Kyungmin; Kim, Yun Tae; Heo, Jun Hyuk; Lee, Chang Young; Lee, Jung Heon; Bien, Franklin; Park, Jang-Ung.

In: Science Advances, Vol. 4, No. 1, eaap9841, 01.01.2018.

Research output: Contribution to journalArticle

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AU - Heo, Jun Hyuk

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AU - Lee, Jung Heon

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