Soft tissue substitutes to increase gingival thickness

Histologic and volumetric analyses in dogs

Young Woo Song, Sungtae Kim, Tobias Waller, Jae Kook Cha, Sung Won Cho, Ui-Won Jung, Daniel S. Thoma

Research output: Contribution to journalArticle

Abstract

Objectives: To evaluate the histologic and volumetric changes of gingival tissues following grafting with collagen-based matrices at labial aspect of teeth in canines. Materials and Methods: Gingival augmentation was performed in the mandibular incisor area using two types of xenogeneic cross-linked collagen matrices (CCMs), bovine CCM for BCCM group and porcine CCM for PCCM group, whereas the contralateral sides remained untreated (B-control group and P-control group). Descriptive histology, histometric and volumetric analyses were performed after 12 weeks. For statistical comparison between each test group and respective control group, paired t test was used for histometric analysis, and repeated-measured analysis of variance was used for volumetric analysis (p < 0.05). Results: An increased number of rete pegs and an enhanced formation of new blood vessels were observed at both grafted sites compared to the corresponding control sites. There was statistically significant gain of horizontal thickness only in BCCM group (1.36 ± 0.27 mm vs. 1.26 ± 0.34 mm; p < 0.05) compared to the B-control groups. Conclusion: BCCM was effective for gingival augmentation in terms of horizontal thickness at the labial aspect of teeth at 12 weeks post-surgery.

Original languageEnglish
Pages (from-to)96-104
Number of pages9
JournalJournal of Clinical Periodontology
Volume46
Issue number1
DOIs
Publication statusPublished - 2019 Jan 1

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Collagen
Dogs
Control Groups
Lip
Cuspid
Tissue Transplantation
Incisor
Blood Vessels
Histology
Analysis of Variance
Tooth
Swine

All Science Journal Classification (ASJC) codes

  • Periodontics

Cite this

Song, Young Woo ; Kim, Sungtae ; Waller, Tobias ; Cha, Jae Kook ; Cho, Sung Won ; Jung, Ui-Won ; Thoma, Daniel S. / Soft tissue substitutes to increase gingival thickness : Histologic and volumetric analyses in dogs. In: Journal of Clinical Periodontology. 2019 ; Vol. 46, No. 1. pp. 96-104.
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abstract = "Objectives: To evaluate the histologic and volumetric changes of gingival tissues following grafting with collagen-based matrices at labial aspect of teeth in canines. Materials and Methods: Gingival augmentation was performed in the mandibular incisor area using two types of xenogeneic cross-linked collagen matrices (CCMs), bovine CCM for BCCM group and porcine CCM for PCCM group, whereas the contralateral sides remained untreated (B-control group and P-control group). Descriptive histology, histometric and volumetric analyses were performed after 12 weeks. For statistical comparison between each test group and respective control group, paired t test was used for histometric analysis, and repeated-measured analysis of variance was used for volumetric analysis (p < 0.05). Results: An increased number of rete pegs and an enhanced formation of new blood vessels were observed at both grafted sites compared to the corresponding control sites. There was statistically significant gain of horizontal thickness only in BCCM group (1.36 ± 0.27 mm vs. 1.26 ± 0.34 mm; p < 0.05) compared to the B-control groups. Conclusion: BCCM was effective for gingival augmentation in terms of horizontal thickness at the labial aspect of teeth at 12 weeks post-surgery.",
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Soft tissue substitutes to increase gingival thickness : Histologic and volumetric analyses in dogs. / Song, Young Woo; Kim, Sungtae; Waller, Tobias; Cha, Jae Kook; Cho, Sung Won; Jung, Ui-Won; Thoma, Daniel S.

In: Journal of Clinical Periodontology, Vol. 46, No. 1, 01.01.2019, p. 96-104.

Research output: Contribution to journalArticle

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T2 - Histologic and volumetric analyses in dogs

AU - Song, Young Woo

AU - Kim, Sungtae

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AU - Cha, Jae Kook

AU - Cho, Sung Won

AU - Jung, Ui-Won

AU - Thoma, Daniel S.

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