Solid-phase combinatorial synthesis and cytotoxicity of 3-aryl-2,4-quinazolindiones

Hea Young Park Choo; Mihyun Kim; Sang Kook Lee; Sang Woong Kim; In Kwon Chung

doi:10.1016/S0968-0896(01)00299-1

Solid-phase combinatorial synthesis and cytotoxicity of 3-aryl-2,4-quinazolindiones

Hea Young Park Choo, Mihyun Kim, Sang Kook Lee, Sang Woong Kim, In Kwon Chung

Research output: Contribution to journal › Article

50 Citations (Scopus)

Abstract

A series of 3-aryl-2,4-quinazolinediones with various substitution on aromatic rings has been prepared by solid-phase synthesis. Several compounds showed cytotoxicity on human colon carcinoma (Col2) tested by SRB method.

Original language	English
Pages (from-to)	517-523
Number of pages	7
Journal	Bioorganic and Medicinal Chemistry
Volume	10
Issue number	3
DOIs	https://doi.org/10.1016/S0968-0896(01)00299-1
Publication status	Published - 2002 Feb 11

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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Park Choo, H. Y., Kim, M., Lee, S. K., Woong Kim, S., & Kwon Chung, I. (2002). Solid-phase combinatorial synthesis and cytotoxicity of 3-aryl-2,4-quinazolindiones. Bioorganic and Medicinal Chemistry, 10(3), 517-523. https://doi.org/10.1016/S0968-0896(01)00299-1

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abstract = "A series of 3-aryl-2,4-quinazolinediones with various substitution on aromatic rings has been prepared by solid-phase synthesis. Several compounds showed cytotoxicity on human colon carcinoma (Col2) tested by SRB method.",

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AU - Kwon Chung, In

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