Solid-phase combinatorial synthesis and cytotoxicity of 3-aryl-2,4-quinazolindiones

Hea Young Park Choo, Mihyun Kim, Sang Kook Lee, Sang Woong Kim, In Kwon Chung

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)


A series of 3-aryl-2,4-quinazolinediones with various substitution on aromatic rings has been prepared by solid-phase synthesis. Several compounds showed cytotoxicity on human colon carcinoma (Col2) tested by SRB method.

Original languageEnglish
Pages (from-to)517-523
Number of pages7
JournalBioorganic and Medicinal Chemistry
Issue number3
Publication statusPublished - 2002

Bibliographical note

Funding Information:
This work was supported by a grant from Korea Research Foundation (300-1392).

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry


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