Abstract
Aim: To describe the computed tomography (CT) and magnetic resonance imaging (MRI) findings that differentiate solid pseudopapillary carcinomas (SPC) from benign solid pseudopapillary tumours (SPT) of the pancreas. Materials and methods: Preoperative CT or MRI images for 26 patients (eight patients with SPC and 18 patients with SPT) were retrospectively reviewed. In addition to the general morphological features, the presence of pancreatic duct dilation, vascular invasion, and extrapancreatic metastases were comparatively assessed. Results: There were no significant differences between pancreatic SPC and benign SPT with respect to tumour size, location, capsule thickness, internal composition, and pattern of calcification, nor was there any correlation with the age and gender of the patients. Pancreatic duct dilation was present in four of the eight (50%) SPC patients, and was absent in all benign SPT patients (p = 0.005). Vascular encasement by the tumour (n = 2) and hepatic metastases (n = 2) were also exclusively demonstrated in SPC patients. Multivariate logistic regression analysis showed that pancreatic duct dilation (p = 0.001), vessel encasement (p = 0.027), and metastasis (p = 0.027) were the variables that can be used to differentiate SPC from benign SPT. Conclusion: SPC of the pancreas may help to differentiate from benign SPT using the imaging features of aggressive behaviour of pancreatic duct dilation and vessel encasement with or without extrapancreatic metastases.
| Original language | English |
|---|---|
| Pages (from-to) | 1006-1014 |
| Number of pages | 9 |
| Journal | Clinical Radiology |
| Volume | 63 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2008 Sep 1 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
Cite this
}
Solid pseudopapillary carcinoma of the pancreas : differentiation from benign solid pseudopapillary tumour using CT and MRI. / Lee, J. H.; Yu, J. S.; Kim, H.; Kim, J. K.; Kim, T. H.; Kim, K. W.; Park, M. S.; Kim, J. H.; Kim, Y. B.; Park, C.
In: Clinical Radiology, Vol. 63, No. 9, 01.09.2008, p. 1006-1014.Research output: Contribution to journal › Article
TY - JOUR
T1 - Solid pseudopapillary carcinoma of the pancreas
T2 - differentiation from benign solid pseudopapillary tumour using CT and MRI
AU - Lee, J. H.
AU - Yu, J. S.
AU - Kim, H.
AU - Kim, J. K.
AU - Kim, T. H.
AU - Kim, K. W.
AU - Park, M. S.
AU - Kim, J. H.
AU - Kim, Y. B.
AU - Park, C.
PY - 2008/9/1
Y1 - 2008/9/1
N2 - Aim: To describe the computed tomography (CT) and magnetic resonance imaging (MRI) findings that differentiate solid pseudopapillary carcinomas (SPC) from benign solid pseudopapillary tumours (SPT) of the pancreas. Materials and methods: Preoperative CT or MRI images for 26 patients (eight patients with SPC and 18 patients with SPT) were retrospectively reviewed. In addition to the general morphological features, the presence of pancreatic duct dilation, vascular invasion, and extrapancreatic metastases were comparatively assessed. Results: There were no significant differences between pancreatic SPC and benign SPT with respect to tumour size, location, capsule thickness, internal composition, and pattern of calcification, nor was there any correlation with the age and gender of the patients. Pancreatic duct dilation was present in four of the eight (50%) SPC patients, and was absent in all benign SPT patients (p = 0.005). Vascular encasement by the tumour (n = 2) and hepatic metastases (n = 2) were also exclusively demonstrated in SPC patients. Multivariate logistic regression analysis showed that pancreatic duct dilation (p = 0.001), vessel encasement (p = 0.027), and metastasis (p = 0.027) were the variables that can be used to differentiate SPC from benign SPT. Conclusion: SPC of the pancreas may help to differentiate from benign SPT using the imaging features of aggressive behaviour of pancreatic duct dilation and vessel encasement with or without extrapancreatic metastases.
AB - Aim: To describe the computed tomography (CT) and magnetic resonance imaging (MRI) findings that differentiate solid pseudopapillary carcinomas (SPC) from benign solid pseudopapillary tumours (SPT) of the pancreas. Materials and methods: Preoperative CT or MRI images for 26 patients (eight patients with SPC and 18 patients with SPT) were retrospectively reviewed. In addition to the general morphological features, the presence of pancreatic duct dilation, vascular invasion, and extrapancreatic metastases were comparatively assessed. Results: There were no significant differences between pancreatic SPC and benign SPT with respect to tumour size, location, capsule thickness, internal composition, and pattern of calcification, nor was there any correlation with the age and gender of the patients. Pancreatic duct dilation was present in four of the eight (50%) SPC patients, and was absent in all benign SPT patients (p = 0.005). Vascular encasement by the tumour (n = 2) and hepatic metastases (n = 2) were also exclusively demonstrated in SPC patients. Multivariate logistic regression analysis showed that pancreatic duct dilation (p = 0.001), vessel encasement (p = 0.027), and metastasis (p = 0.027) were the variables that can be used to differentiate SPC from benign SPT. Conclusion: SPC of the pancreas may help to differentiate from benign SPT using the imaging features of aggressive behaviour of pancreatic duct dilation and vessel encasement with or without extrapancreatic metastases.
UR - http://www.scopus.com/inward/record.url?scp=49349096319&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=49349096319&partnerID=8YFLogxK
U2 - 10.1016/j.crad.2008.04.007
DO - 10.1016/j.crad.2008.04.007
M3 - Article
C2 - 18718230
AN - SCOPUS:49349096319
VL - 63
SP - 1006
EP - 1014
JO - Clinical Radiology
JF - Clinical Radiology
SN - 0009-9260
IS - 9
ER -