Due to a growing interest in aza-fused polyaromatic systems among various sciences, enormous attention has been continuously paid to design and synthesize novel chemotypes of N -fused hetero cycles. During the course of continued efforts in this line, it was found that divergent access to new polycyclic N -fused heteroaromatics was enabled by choice of reaction solvent. Described herein are solvent-controlled selective approaches to three novel N -fused azacycles, benzo-[ d ]imidazole-pyrrolo[1,2- a ]pyrazine hybrids, under mild conditions. The plausible reaction mechanism for each class of compound is suggested as well.
All Science Journal Classification (ASJC) codes
- Organic Chemistry