As a green alternative to classical homogeneous catalyst in toluene in closed vessels, the intermolecular hydroacylation of 1-alkenes with aldehydes by Rh(I) complex (Wilkinson catalyst) can be realized efficiently under solvent-free conditions. When coupled to microwave activation, it results in a serious improvement when compared to classical conditions.
Bibliographical noteFunding Information:
This work was supported by the National Research Laboratory (2000-N-NL-01-C-271) Program administrated by the Ministry of Science and Technology, and Brain Korea 21 project.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry