Spatial epidemiology of dry eye disease: Findings from South Korea

Sun Bi Um, Na H. Kim, Hyung K. Lee, Jong S. Song, Hyeon C. Kim

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Background: DED rate maps from diverse regions may allow us to understand world-wide spreading pattern of the disease. Only few studies compared the prevalence of DED between geographical regions in non-spatial context. Therefore, we examined the spatial epidemiological pattern of DED prevalence in South Korea using a nationally representative sample.Methods: We analyzed 16,431 Korean adults aged 30 years or older of the 5th Korea National Health and Nutrition Examination Survey. DED was defined as previously diagnosed by an ophthalmologist as well as symptoms experienced. Multiple logistic regression analysis was used to assess the spatial pattern in the prevalence of DED, and effects of environmental factors.Results: Among seven metropolitan cities and nine provinces, three metropolitan cities located in the southeast of Korea revealed the highest prevalence of DED. After adjusting for sex, age and survey year, people living in urban areas had higher risk of having DED. Adjusted odds ratio for having previously diagnosed DED was 1.677 (95% CI 1.299-2.166) for metropolitan cities and 1.580 (95% CI 1.215-2.055) for other cities compared to rural areas. Corresponding odds ratio for presenting DED symptoms was 1.388 (95% CI 1.090-1.766) for metropolitan cities and 1.271 (95% CI 0.999-1.617) for other cities. Lower humidity and longer sunshine duration were significantly associated with DED. Among air pollutants, SO2 was associated with DED, while NO2, O3, CO, and PM10 were not.Conclusion: Our findings suggest that prevalence of DED can be affected by the degree of urbanization and environmental factors such as humidity and sunshine duration.

Original languageEnglish
Article number31
JournalInternational Journal of Health Geographics
Volume13
Issue number1
DOIs
Publication statusPublished - 2014 Aug 15

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Epidemiology
Republic of Korea
Eye Diseases
Atmospheric humidity
Geographical regions
Nutrition
Regression analysis
Logistics
Sunlight
Health
Korea
Humidity
Air
Odds Ratio
Air Pollutants
Urbanization
Nutrition Surveys
Carbon Monoxide
South Korea
Cross-Sectional Studies

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Business, Management and Accounting(all)
  • Public Health, Environmental and Occupational Health

Cite this

Um, Sun Bi ; Kim, Na H. ; Lee, Hyung K. ; Song, Jong S. ; Kim, Hyeon C. / Spatial epidemiology of dry eye disease : Findings from South Korea. In: International Journal of Health Geographics. 2014 ; Vol. 13, No. 1.
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Spatial epidemiology of dry eye disease : Findings from South Korea. / Um, Sun Bi; Kim, Na H.; Lee, Hyung K.; Song, Jong S.; Kim, Hyeon C.

In: International Journal of Health Geographics, Vol. 13, No. 1, 31, 15.08.2014.

Research output: Contribution to journalArticle

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