Spatially and temporally controlled hydrogels for tissue engineering

Jeroen Leijten; Jungmok Seo; Kan Yue; Grissel Trujillo-de Santiago; Ali Tamayol; Guillermo U. Ruiz-Esparza; Su Ryon Shin; Roholah Sharifi; Iman Noshadi; Mario Moisés Álvarez; Yu Shrike Zhang; Ali Khademhosseini

doi:10.1016/j.mser.2017.07.001

Spatially and temporally controlled hydrogels for tissue engineering

Jeroen Leijten, Jungmok Seo, Kan Yue, Grissel Trujillo-de Santiago, Ali Tamayol, Guillermo U. Ruiz-Esparza, Su Ryon Shin, Roholah Sharifi, Iman Noshadi, Mario Moisés Álvarez, Yu Shrike Zhang, Ali Khademhosseini

Department of Electrical and Electronic Engineering

Research output: Contribution to journal › Review article › peer-review

133 Citations (Scopus)

Abstract

Recent years have seen tremendous advances in the field of hydrogel-based biomaterials. One of the most prominent revolutions in this field has been the integration of elements or techniques that enable spatial and temporal control over hydrogels’ properties and functions. Here, we critically review the emerging progress of spatiotemporal control over biomaterial properties towards the development of functional engineered tissue constructs. Specifically, we will highlight the main advances in the spatial control of biomaterials, such as surface modification, microfabrication, photo-patterning, and bioprinting, as well as advances in the temporal control of biomaterials, such as controlled release of molecules, photocleaving of proteins, and controlled hydrogel degradation. We believe that the development and integration of these techniques will drive the evolution of next-generation engineered tissues.

Original language	English
Pages (from-to)	1-35
Number of pages	35
Journal	Materials Science and Engineering R: Reports
Volume	119
DOIs	https://doi.org/10.1016/j.mser.2017.07.001
Publication status	Published - 2017 Sept

Bibliographical note

Funding Information:
This paper was supported by National Science Foundation (EFRI-1240443), ONR PECASE Award, the Department of Defense Congressionally Directed Medical Research Programs (OR110196) and the National Institutes of Health (AR066193, AR063194, HL092836, DE019024, EB012597, AR057837, DE021468, DE022376, HL099073, EB008392, AR069564, AR007505, HL137193, and EB024403). Dr. Leijten acknowledges financial support from Innovative Research Incentives Scheme Veni #14328 of the Netherlands Organization for Scientific Research (NWO). Dr. Seo was partially supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2016R1A6A3A03006491). Dr. Zhang acknowledges the National Cancer Institute of the National Institutes of Health Pathway to Independence Award (K99CA201603). This paper has been partially funded by the Tec de Monterrey and MIT Nanotechnology Program.

Publisher Copyright:
© 2017 Elsevier B.V.

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1016/j.mser.2017.07.001

Cite this

@article{c7c907f6b2ca40daaeee57253016c650,

title = "Spatially and temporally controlled hydrogels for tissue engineering",

abstract = "Recent years have seen tremendous advances in the field of hydrogel-based biomaterials. One of the most prominent revolutions in this field has been the integration of elements or techniques that enable spatial and temporal control over hydrogels{\textquoteright} properties and functions. Here, we critically review the emerging progress of spatiotemporal control over biomaterial properties towards the development of functional engineered tissue constructs. Specifically, we will highlight the main advances in the spatial control of biomaterials, such as surface modification, microfabrication, photo-patterning, and bioprinting, as well as advances in the temporal control of biomaterials, such as controlled release of molecules, photocleaving of proteins, and controlled hydrogel degradation. We believe that the development and integration of these techniques will drive the evolution of next-generation engineered tissues.",

author = "Jeroen Leijten and Jungmok Seo and Kan Yue and {Trujillo-de Santiago}, Grissel and Ali Tamayol and Ruiz-Esparza, {Guillermo U.} and Shin, {Su Ryon} and Roholah Sharifi and Iman Noshadi and {\'A}lvarez, {Mario Mois{\'e}s} and Zhang, {Yu Shrike} and Ali Khademhosseini",

note = "Funding Information: This paper was supported by National Science Foundation (EFRI-1240443), ONR PECASE Award, the Department of Defense Congressionally Directed Medical Research Programs (OR110196) and the National Institutes of Health (AR066193, AR063194, HL092836, DE019024, EB012597, AR057837, DE021468, DE022376, HL099073, EB008392, AR069564, AR007505, HL137193, and EB024403). Dr. Leijten acknowledges financial support from Innovative Research Incentives Scheme Veni #14328 of the Netherlands Organization for Scientific Research (NWO). Dr. Seo was partially supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2016R1A6A3A03006491). Dr. Zhang acknowledges the National Cancer Institute of the National Institutes of Health Pathway to Independence Award (K99CA201603). This paper has been partially funded by the Tec de Monterrey and MIT Nanotechnology Program. Publisher Copyright: {\textcopyright} 2017 Elsevier B.V.",

year = "2017",

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doi = "10.1016/j.mser.2017.07.001",

language = "English",

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AU - Leijten, Jeroen

AU - Seo, Jungmok

AU - Yue, Kan

AU - Trujillo-de Santiago, Grissel

AU - Tamayol, Ali

AU - Ruiz-Esparza, Guillermo U.

AU - Shin, Su Ryon

AU - Sharifi, Roholah

AU - Noshadi, Iman

AU - Álvarez, Mario Moisés

AU - Zhang, Yu Shrike

AU - Khademhosseini, Ali

N1 - Funding Information: This paper was supported by National Science Foundation (EFRI-1240443), ONR PECASE Award, the Department of Defense Congressionally Directed Medical Research Programs (OR110196) and the National Institutes of Health (AR066193, AR063194, HL092836, DE019024, EB012597, AR057837, DE021468, DE022376, HL099073, EB008392, AR069564, AR007505, HL137193, and EB024403). Dr. Leijten acknowledges financial support from Innovative Research Incentives Scheme Veni #14328 of the Netherlands Organization for Scientific Research (NWO). Dr. Seo was partially supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2016R1A6A3A03006491). Dr. Zhang acknowledges the National Cancer Institute of the National Institutes of Health Pathway to Independence Award (K99CA201603). This paper has been partially funded by the Tec de Monterrey and MIT Nanotechnology Program. Publisher Copyright: © 2017 Elsevier B.V.

PY - 2017/9

Y1 - 2017/9

N2 - Recent years have seen tremendous advances in the field of hydrogel-based biomaterials. One of the most prominent revolutions in this field has been the integration of elements or techniques that enable spatial and temporal control over hydrogels’ properties and functions. Here, we critically review the emerging progress of spatiotemporal control over biomaterial properties towards the development of functional engineered tissue constructs. Specifically, we will highlight the main advances in the spatial control of biomaterials, such as surface modification, microfabrication, photo-patterning, and bioprinting, as well as advances in the temporal control of biomaterials, such as controlled release of molecules, photocleaving of proteins, and controlled hydrogel degradation. We believe that the development and integration of these techniques will drive the evolution of next-generation engineered tissues.

AB - Recent years have seen tremendous advances in the field of hydrogel-based biomaterials. One of the most prominent revolutions in this field has been the integration of elements or techniques that enable spatial and temporal control over hydrogels’ properties and functions. Here, we critically review the emerging progress of spatiotemporal control over biomaterial properties towards the development of functional engineered tissue constructs. Specifically, we will highlight the main advances in the spatial control of biomaterials, such as surface modification, microfabrication, photo-patterning, and bioprinting, as well as advances in the temporal control of biomaterials, such as controlled release of molecules, photocleaving of proteins, and controlled hydrogel degradation. We believe that the development and integration of these techniques will drive the evolution of next-generation engineered tissues.

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DO - 10.1016/j.mser.2017.07.001

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SN - 0927-796X

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SP - 1

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JO - Materials Science and Engineering: R: Reports

JF - Materials Science and Engineering: R: Reports

ER -

Spatially and temporally controlled hydrogels for tissue engineering

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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