The understanding of species distribution and inducible macrolide resistance in the Mycobacterium fortuitum complex (MFC) is limited. Of 90 mostly respiratory MFC clinical isolates, half were M. fortuitum, followed by M. peregrinum, M. porcinum, M. septicum, and M. conceptionense. Most M. fortuitum, M. porcinum, and M. septicum isolates were inducibly resistant to clarithromycin, whereas two-thirds of the M. peregrinum isolates were clarithromycin susceptible. Clarithromycin-resistant M. fortuitum isolates exhibited common mutations of erm(39), potentially involved in clarithromycin resistance.
Bibliographical noteFunding Information:
This work was supported by the National Research Foundation of Korea (NRF) funded by the South Korea government (MSIT) (NRF-2018R1A2A1A05018309).
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Infectious Diseases