Spheroform: Therapeutic spheroid-forming nanotextured surfaces inspired by desert beetle physosterna cribripes

Mihyun Lee, Kisuk Yang, Yong Hwa Hwang, Youngro Byun, Dong Yun Lee, Seung Woo Cho, Haeshin Lee

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

An approach is presented to create arrays of quasi-spherical microdroplets by surfaces called "spheroform" inspired by micro-/nanostructures found in the back of the Namib desert beetle. Spheroform is fabricated by microarray formation of catecholamine polymers on the superhydrophobic background. Spheroform is able to precisely control spheroid sizes of therapeutic islet cells and mesenchymal stem cells. The therapeutic spheroids exhibit improved biochemical activities.

Original languageEnglish
Pages (from-to)511-515
Number of pages5
JournalAdvanced Healthcare Materials
Volume4
Issue number4
DOIs
Publication statusPublished - 2015 Mar 1

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science

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