Spheroform

Therapeutic spheroid-forming nanotextured surfaces inspired by desert beetle physosterna cribripes

Mihyun Lee, Kisuk Yang, Yong Hwa Hwang, Youngro Byun, Dong Yun Lee, Seung-Woo Cho, Haeshin Lee

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

An approach is presented to create arrays of quasi-spherical microdroplets by surfaces called "spheroform" inspired by micro-/nanostructures found in the back of the Namib desert beetle. Spheroform is fabricated by microarray formation of catecholamine polymers on the superhydrophobic background. Spheroform is able to precisely control spheroid sizes of therapeutic islet cells and mesenchymal stem cells. The therapeutic spheroids exhibit improved biochemical activities.

Original languageEnglish
Pages (from-to)511-515
Number of pages5
JournalAdvanced healthcare materials
Volume4
Issue number4
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Beetles
Microarrays
Stem cells
Catecholamines
Nanostructures
Polymers
Mesenchymal Stromal Cells
Islets of Langerhans
Therapeutics

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science

Cite this

Lee, Mihyun ; Yang, Kisuk ; Hwang, Yong Hwa ; Byun, Youngro ; Lee, Dong Yun ; Cho, Seung-Woo ; Lee, Haeshin. / Spheroform : Therapeutic spheroid-forming nanotextured surfaces inspired by desert beetle physosterna cribripes. In: Advanced healthcare materials. 2015 ; Vol. 4, No. 4. pp. 511-515.
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Spheroform : Therapeutic spheroid-forming nanotextured surfaces inspired by desert beetle physosterna cribripes. / Lee, Mihyun; Yang, Kisuk; Hwang, Yong Hwa; Byun, Youngro; Lee, Dong Yun; Cho, Seung-Woo; Lee, Haeshin.

In: Advanced healthcare materials, Vol. 4, No. 4, 01.01.2015, p. 511-515.

Research output: Contribution to journalArticle

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AU - Lee, Haeshin

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