Stabilization of an α helix by β-sheet-mediated self-assembly of a macrocyclic peptide

Yong-beom Lim, Kyung Soo Moon, Myongsoo Lee

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

(Figure Presented) Protein roll call: Peptide-based building blocks, in which both an α-helix-forming segment segment are located within a single macrocyclic structure, self-assemble into α-helix proteins. This approach provides a starting point for developing artificial proteins that can modulate α-helix-mediated interactions occurring in a multivalent fashion.

Original languageEnglish
Pages (from-to)1601-1605
Number of pages5
JournalAngewandte Chemie - International Edition
Volume48
Issue number9
DOIs
Publication statusPublished - 2009 Feb 16

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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