The biocompatible polyurethane acrylate (PUA) nanopillars were fabricated by soft lithography using three different sizes of nanobeads (350, 500, and 1000 nm), and the human adipose-derived stem cells (hASCs) were cultured on the nanopillars. The hASCs and their various behaviors, such as cytoplasmic projections, migration, and morphology, were observed by high resolution images using a scanning electron microscope (SEM). With the accurate analysis by SEM for the controlled sizes of nanopillars, the deflections are observed at pillars fabricated with 350- and 500-nm nanobeads. These high-resolution images could offer crucial information to elucidate the complicated correlations between nanopillars and the cells, such as morphology and cytoplasmic projections.
|Publication status||Published - 2020 Dec|
Bibliographical noteFunding Information:
This research was supported by Research Program through the National Institute of Ecology (NIE-Basic Research-2020-18) and also supported by National Research Foundation (NRF) grant funded by the Ministry of Education, under “Basic Science Research Program” (NRF-2017R1D1A1B04033182).
© 2020, The Author(s).
All Science Journal Classification (ASJC) codes
- Applied Microbiology and Biotechnology