Stent evaluation with optical coherence tomography

Seung Yul Lee, Myeongki Hong

Research output: Contribution to journalReview article

22 Citations (Scopus)

Abstract

Optical coherence tomography (OCT) has been recently applied to investigate coronary artery disease in interventional cardiology. Compared to intravascular ultrasound, OCT is able to visualize various vascular structures more clearly with higher resolution. Several validation studies have shown that OCT is more accurate in evaluating neointimal tissue after coronary stent implantation than intravascular ultrasound. Novel findings on OCT evaluation include the detection of strut coverage and the characterization of neointimal tissue in an in-vivo setting. In a previous study, neointimal healing of stent strut was pathologically the most important factor associated with stent thrombosis, a fatal complication, in patients treated with drug-eluting stent (DES). Recently, OCT-defined coverage of a stent strut was proposed to be related with clinical safety in DES-treated patients. Neoatherosclerosis is an atheromatous change of neointimal tissue within the stented segment. Clinical studies using OCT revealed neoatherosclerosis contributed to late-phase luminal narrowing after stent implantation. Like de novo native coronary lesions, the clinical presentation of OCT-derived neoatherosclerosis varied from stable angina to acute coronary syndrome including late stent thrombosis. Thus, early identification of neoatherosclerosis with OCT may predict clinical deterioration in patients treated with coronary stent. Additionally, intravascular OCT evaluation provides additive information about the performance of coronary stent. In the near future, new advances in OCT technology will help reduce complications with stent therapy and accelerating in the study of interventional cardiology.

Original languageEnglish
Pages (from-to)1075-1083
Number of pages9
JournalYonsei Medical Journal
Volume54
Issue number5
DOIs
Publication statusPublished - 2013 Sep 1

Fingerprint

Optical Coherence Tomography
Stents
Drug-Eluting Stents
Cardiology
Thrombosis
Stable Angina
Validation Studies
Acute Coronary Syndrome
Blood Vessels
Coronary Artery Disease
Technology
Safety

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Lee, Seung Yul ; Hong, Myeongki. / Stent evaluation with optical coherence tomography. In: Yonsei Medical Journal. 2013 ; Vol. 54, No. 5. pp. 1075-1083.
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Stent evaluation with optical coherence tomography. / Lee, Seung Yul; Hong, Myeongki.

In: Yonsei Medical Journal, Vol. 54, No. 5, 01.09.2013, p. 1075-1083.

Research output: Contribution to journalReview article

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