Stereochemical assignment of five new lignan glycosides from Viscum album by NMR study combined with CD spectroscopy

Nguyen Xuan Nhiem, Hwa Young Lee, Nan Young Kim, Seon Ju Park, Eun Sil Kim, Jeong Eun Han, Heejung Yang, Seung Hyun Kim

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11 Citations (Scopus)


The chemical study of the leaves and twigs of Viscum album led to the isolation of five new lignan glycosides, namely, ligalbumosides A-E (2-6) and one known lignan glycoside, alangilignoside C (1). The structures of five new lignan glycosides were determined to be (7R,8S,8'S)-4,9,4'-trihydroxy-3,5,3',5'- tetramethoxy-7,9'-epoxylignan 9-O-β-D-glucopyranoside (2), (7S,8S,7'S,8'R)-4,9,4'-trihydroxy-3,5,3',5',7'-pentamethoxy-7,9'-epoxylignan 9-O-β-D-glucopyranoside (3), (7R,8R,7'S,8'S)-4,9,4'-trihydroxy-3,5,3',5', 7'-pentamethoxy-7,9'-epoxylignan 9-O-β-D-glucopyranoside (4), (7S,8R,7'S,8'R)-4,9,4'-trihydroxy-3,5,3',5',7'-pentamethoxy-7,9'-epoxylignan 9-O-β-D-glucopyranoside (5), and (7R,8S,7'R,8'S)-4,9,4',7'-tetrahydroxy-3, 5,3',5'-tetramethoxy-7,9'-epoxylignan 9-O-β-D-glucopyranoside (6) using 1D-, 2D-NMR, and CD spectra, chemical methods, as well as comparing the results with those reported in the literature.

Original languageEnglish
Pages (from-to)772-777
Number of pages6
JournalMagnetic Resonance in Chemistry
Issue number11
Publication statusPublished - 2012 Nov 1


All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Science(all)

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