Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp. KORDI-3973

Hee Jae Shin, Tae Sik Kim, Hyi Seung Lee, Jung Youl Park, In Kwon Choi, Ho Jeong Kwon

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Streptopyrrolidine, a benzyl pyrrolidine derivative, was isolated as an angiogenesis inhibitor from the fermentation broth of a marine Streptomyces sp. isolated from the deep sea sediment. Its structure was elucidated by extensive 2D NMR and mass spectroscopic analyses. Streptopyrrolidine exhibited significant anti-angiogenesis activity.

Original languageEnglish
Pages (from-to)2363-2366
Number of pages4
JournalPhytochemistry
Volume69
Issue number12
DOIs
Publication statusPublished - 2008 Sep

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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