Subcategorization of Ultrasonographic BI-RADS Category 4: Positive Predictive Value and Clinical Factors Affecting It

Jung Hyun Yoon, Min Jung Kim, Hee Jung Moon, Jin Young Kwak, Eun Kyung Kim

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

The objective of this study was to evaluate the positive predictive value (PPV) in ultrasonographically (US)-detected breast lesions of BI-RADS category 4a, 4b and 4c and to find how various clinical factors influenced the PPV of category 4. A total of 2142 women with 2430 breast lesions diagnosed on US as BI-RADS category 4 and underwent biopsy were included. Among them, 452 (18.6%) were pathologically confirmed as malignancy. PPV of each US BI-RADS subcategory was 7.6% (149/1963) for category 4a, 37.8% (68/180) for category 4b and 81.9% (235/287) for category 4c. Several clinical factors were more significantly seen in malignancy of category 4a and 4b, whereas none of the factors showed significance in category 4c. Subcategorization of category 4 is a feasible method in predicting malignancy in which patients' age, lack of multiplicity and symptoms affected the PPV of category 4 lesions. (E-mail: ekkim@yuhs.ac).

Original languageEnglish
Pages (from-to)693-699
Number of pages7
JournalUltrasound in Medicine and Biology
Volume37
Issue number5
DOIs
Publication statusPublished - 2011 May

Bibliographical note

Funding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology ( 2009-0067048 ).

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics

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