Successful use of cyclosporin A in severe Schönlein-Henoch nephritis resistant to both methylprednisolone pulse and azathioprine

Jaeil Shin, Jee Min Park, Jae Seung Lee, Ji Hong Kim, Pyung Kil Kim, Hyeon Joo Jeong

Research output: Contribution to journalArticle

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Abstract

Schönlein-Henoch nephritis (SHN) usually presents with micro-haematuria or mild proteinuria but can be associated with heavy proteinuria and nephrotic or acute nephritic syndrome. Although the treatment of SHN is still under debate, it has been suggested that cyclosporin A (CsA) may be beneficial in children with severe SHN, as reported by Ronkainen et al. (Pediatr Nephrol 18:1138-1142, 2003) and Someya et al. (Pediatr Int 46:111-113, 2004). However, histological effects of CsA on severe SHN had not been evaluated in their evaluations. We report the successful use of CsA in a male patient with severe SHN with nephrotic-range proteinuria, who failed to respond to methylprednisolone pulse and azathioprine therapy.

Original languageEnglish
Pages (from-to)759-760
Number of pages2
JournalClinical Rheumatology
Volume25
Issue number5
DOIs
Publication statusPublished - 2006 Sep 1

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Nephritis
Methylprednisolone
Azathioprine
Cyclosporine
Proteinuria
Hematuria
Kidney
Therapeutics

All Science Journal Classification (ASJC) codes

  • Rheumatology

Cite this

Shin, Jaeil ; Park, Jee Min ; Lee, Jae Seung ; Kim, Ji Hong ; Kim, Pyung Kil ; Jeong, Hyeon Joo. / Successful use of cyclosporin A in severe Schönlein-Henoch nephritis resistant to both methylprednisolone pulse and azathioprine. In: Clinical Rheumatology. 2006 ; Vol. 25, No. 5. pp. 759-760.
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Successful use of cyclosporin A in severe Schönlein-Henoch nephritis resistant to both methylprednisolone pulse and azathioprine. / Shin, Jaeil; Park, Jee Min; Lee, Jae Seung; Kim, Ji Hong; Kim, Pyung Kil; Jeong, Hyeon Joo.

In: Clinical Rheumatology, Vol. 25, No. 5, 01.09.2006, p. 759-760.

Research output: Contribution to journalArticle

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