Supramolecular micelle from amphiphilic Mn(III)-porphyrin derivatives as a potential MRI contrast agent

Kwangmo Choi, Do Hyung Lee, Woo Dong Jang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Amphiphilic porphyrin derivatives have been synthesized and characterized by 1H NMR and MALDI-TOF-MS. All porphyrin derivatives showed very high solubility to aqueous medium as well as hydrophobic organic solvent. The UVvis absorption of the porphyrin derivatives showed significant broadness and decrease of maximum intensity of absorption in aqueous solution. SEM experiment showed the formation of spherical micellar structure. The T1 relaxation time of aqueous medium was drastically decreased in the presence of Mn(III)-porphyrin derivative, indicating that the supramolecular micelle has strong possibility to use as a T1 contrast agent.

Original languageEnglish
Pages (from-to)639-644
Number of pages6
JournalBulletin of the Korean Chemical Society
Volume31
Issue number3
DOIs
Publication statusPublished - 2010 Mar 1

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this