Abstract
The influence of microenvironments on the culture of osteoblast-like cells (MG-63) has been investigated using parylene films with different surfaces, such as parylene-N film, UV-modified parylene-N film, functional parylene film with amine groups (parylene-A), and UV-modified parylene-A film. In this work, parylene-N film was found to induce dramatic changes in cell adhesion and cell viability before and after UV-treatment with respect to the culture of osteoblast-like cells (MG-63). The influences of such a chemical environment on cell culture were investigated in relation to the cell proliferation (viability and proliferation rate) and the cell physiology (cell cycle, protein synthesis, and differentiation) of cells grown on parylene-N film, UV-modified parylene-N film, parylene-A film, and UV-modified parylene-A film in comparison with cells grown on a polystyrene surface.
| Original language | English |
|---|---|
| Pages (from-to) | 277-285 |
| Number of pages | 9 |
| Journal | Applied Surface Science |
| Volume | 378 |
| DOIs | |
| Publication status | Published - 2016 Aug 15 |
Bibliographical note
Funding Information:This research was supported by the National Research Foundation of Korea ( 2014M3A9E5073818 , 2015R1D1A1A01057737 and 2011-0020285 ).
Publisher Copyright:
© 2016 Elsevier B.V. All rights reserved.
All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Condensed Matter Physics
- Physics and Astronomy(all)
- Surfaces and Interfaces
- Surfaces, Coatings and Films