Surface-modified magnetite nanoparticles for hyperthermia: Preparation, characterization, and cytotoxicity studies

D. H. Kim, S. H. Lee, K. H. Im, K. N. Kim, K. M. Kim, I. B. Shim, M. H. Lee, Y. K. Lee

Research output: Contribution to journalArticle

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Abstract

Biocompatible magnetic nanoparticles could be selected for smart hyperthermia. The magnetic particles should have a narrow size distribution and surface modified with biocompatible materials. In this study, the effects of surface modification in nano-magnetite were evaluated by characterization and cell response. The synthesized magnetite exhibited a mean diameter of 10.3 ± 2.6 nm. The temperature change under alternating magnetic field and saturation magnetization (Ms) was ΔT = 23 °C, Ms = 25.6 emu/g and ΔT = 12 °C, Ms = 16.4 emu/g in chitosan and starch coated magnetite, respectively. In cytotoxic test, the viability of L929 cells was the greatest value 93.67% in chitosan coated magnetic particles. The exothermic and biocompatible chitosan coated magnetite will be selected for optimized hyperthermic thermoseed.

Original languageEnglish
Pages (from-to)e242-e246
JournalCurrent Applied Physics
Volume6
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 2006 Aug 1

Fingerprint

Magnetite Nanoparticles
Ferrosoferric Oxide
Magnetite nanoparticles
hyperthermia
Magnetite
Cytotoxicity
magnetite
Chitosan
nanoparticles
preparation
Saturation magnetization
starches
Biocompatible Materials
cells
Starch
viability
Biomaterials
Surface treatment
Magnetic fields
Nanoparticles

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Physics and Astronomy(all)

Cite this

Kim, D. H. ; Lee, S. H. ; Im, K. H. ; Kim, K. N. ; Kim, K. M. ; Shim, I. B. ; Lee, M. H. ; Lee, Y. K. / Surface-modified magnetite nanoparticles for hyperthermia : Preparation, characterization, and cytotoxicity studies. In: Current Applied Physics. 2006 ; Vol. 6, No. SUPPL. 1. pp. e242-e246.
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Surface-modified magnetite nanoparticles for hyperthermia : Preparation, characterization, and cytotoxicity studies. / Kim, D. H.; Lee, S. H.; Im, K. H.; Kim, K. N.; Kim, K. M.; Shim, I. B.; Lee, M. H.; Lee, Y. K.

In: Current Applied Physics, Vol. 6, No. SUPPL. 1, 01.08.2006, p. e242-e246.

Research output: Contribution to journalArticle

TY - JOUR

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AU - Kim, D. H.

AU - Lee, S. H.

AU - Im, K. H.

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AU - Kim, K. M.

AU - Shim, I. B.

AU - Lee, M. H.

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