Surface Pattern Analysis of Microplastics and Their Impact on Human-Derived Cells

Seora Han, Junah Bang, Daheui Choi, Jangsun Hwang, Taeho Kim, Yoogyeong Oh, Youngdeok Hwang, Jonghoon Choi, Jinkee Hong

Research output: Contribution to journalArticlepeer-review

Abstract

Plastic is produced, used, and accumulated exponentially. Humans can take it through the food chain, and microplastics can be potentially toxic to humans. In this study, we analyzed the surface patterns of microplastics and their effects on humans using polyvinyl chloride (PVC) and acrylonitrile butadiene styrene (ABS). The surface analysis of these microplastics will be used as a standardized measurement method for microplastic detection and will be used as an indicator of the impact of environmental pollution caused by microplastics on humans. We have used a statistical method to analyze the shape of the milled microplastics and estimated the local curvature for each plastic type and found that PVC microplastics have a more rugged shape than the ABS microplastics. We also analyzed the toxicity of PVC and ABS microplastics. Larger PVC tended to induce the release of interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α). Smaller ABS induced the release of IL-6 at high concentrations. However, larger ABS tended to induce the release of TNF-α at all concentrations. Thus, we concluded that microplastics can induce immune responses.

Original languageEnglish
Pages (from-to)4541-4550
Number of pages10
JournalACS Applied Polymer Materials
Volume2
Issue number11
DOIs
Publication statusPublished - 2020 Nov 13

Bibliographical note

Funding Information:
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2017R1E1A1A01074343).

Publisher Copyright:
© 2020 ACS. All rights reserved.

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics
  • Process Chemistry and Technology
  • Organic Chemistry

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