@inproceedings{61d1a3c65ce64b778ac6811f2e73009e,
title = "Surface plasmon enhanced cell microscopy with blocked random spatial activation",
abstract = "We present surface plasmon enhanced fluorescence microscopy with random spatial sampling using patterned block of silver nanoislands. Rigorous coupled wave analysis was performed to confirm near-field localization on nanoislands. Random nanoislands were fabricated in silver by temperature annealing. By analyzing random near-field distribution, average size of localized fields was found to be on the order of 135 nm. Randomly localized near-fields were used to spatially sample F-actin of J774 cells (mouse macrophage cell-line). Image deconvolution algorithm based on linear imaging theory was established for stochastic estimation of fluorescent molecular distribution. The alignment between near-field distribution and raw image was performed by the patterned block. The achieved resolution is dependent upon factors including the size of localized fields and estimated to be 100-150 nm.",
author = "Taehwang Son and Youngjin Oh and Wonju Lee and Heejin Yang and Donghyun Kim",
year = "2016",
doi = "10.1117/12.2210753",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Cartwright, {Alexander N.} and Nicolau, {Dan V.}",
booktitle = "Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII",
address = "United States",
note = "Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII ; Conference date: 15-02-2016 Through 17-02-2016",
}