Surgical treatment of carotid body paragangliomas

Outcomes and complications according to the shamblin classification

JaeYoul Lim, Jinna Kim, Sun Ho Kim, Sak Lee, Young Chang Lim, Jae Wook Kim, Eun Chang Choi

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Objectives. The objective of this study was to review our experience in the surgical management of carotid body paragangliomas and evaluate the outcomes and complications according to the Shamblin classification. Methods. Thirteen patients who had been diagnosed and surgically treated for carotid body tumors (CBTs) were enrolled in this study. We reviewed patient demographics, radiographic findings, and surgical outcomes collected from medical records. Results. Fifteen CBTs were found in 13 patients and 13 tumors were resected. Selective preoperative tumor embolization was performed on six patients. The median blood loss, operation time, and hospital stay for these patients were not significantly reduced compared to those without embolization. The median tumor size was 2.3 cm in Shamblin I and II and 4 cm in Shamblin III. The median intraoperative blood loss was 280 mL and 700 mL, respectively (P<0.05). Internal carotid artery ligation with reconstruction was accomplished on three patients (23%), and they all belonged to Shamblin III (38%). One Shamblin III patient (8%) developed transient cerebral ischemia, and postoperative stroke with death occurred in another Shamblin III patient. Postoperative permanent cranial nerve deficit occurred in three patients (23%) who were all in Shamblin III (P=0.03). There were no recurrences or delayed complications at the median follow up of 29 months. Conclusion. Shamblin III had a high risk of postoperative neurovascular complications. Therefore, early detection and prompt surgical resection of CBTs will decrease surgical morbidity.

Original languageEnglish
Pages (from-to)91-95
Number of pages5
JournalClinical and Experimental Otorhinolaryngology
Volume3
Issue number2
DOIs
Publication statusPublished - 2010 Jun 1

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Carotid Body Tumor
Therapeutics
Neoplasms
Cranial Nerves
Transient Ischemic Attack
Internal Carotid Artery
Medical Records
Ligation
Length of Stay
Stroke
Demography
Morbidity

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Surgery

Cite this

Lim, JaeYoul ; Kim, Jinna ; Kim, Sun Ho ; Lee, Sak ; Lim, Young Chang ; Kim, Jae Wook ; Choi, Eun Chang. / Surgical treatment of carotid body paragangliomas : Outcomes and complications according to the shamblin classification. In: Clinical and Experimental Otorhinolaryngology. 2010 ; Vol. 3, No. 2. pp. 91-95.
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Surgical treatment of carotid body paragangliomas : Outcomes and complications according to the shamblin classification. / Lim, JaeYoul; Kim, Jinna; Kim, Sun Ho; Lee, Sak; Lim, Young Chang; Kim, Jae Wook; Choi, Eun Chang.

In: Clinical and Experimental Otorhinolaryngology, Vol. 3, No. 2, 01.06.2010, p. 91-95.

Research output: Contribution to journalArticle

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N2 - Objectives. The objective of this study was to review our experience in the surgical management of carotid body paragangliomas and evaluate the outcomes and complications according to the Shamblin classification. Methods. Thirteen patients who had been diagnosed and surgically treated for carotid body tumors (CBTs) were enrolled in this study. We reviewed patient demographics, radiographic findings, and surgical outcomes collected from medical records. Results. Fifteen CBTs were found in 13 patients and 13 tumors were resected. Selective preoperative tumor embolization was performed on six patients. The median blood loss, operation time, and hospital stay for these patients were not significantly reduced compared to those without embolization. The median tumor size was 2.3 cm in Shamblin I and II and 4 cm in Shamblin III. The median intraoperative blood loss was 280 mL and 700 mL, respectively (P<0.05). Internal carotid artery ligation with reconstruction was accomplished on three patients (23%), and they all belonged to Shamblin III (38%). One Shamblin III patient (8%) developed transient cerebral ischemia, and postoperative stroke with death occurred in another Shamblin III patient. Postoperative permanent cranial nerve deficit occurred in three patients (23%) who were all in Shamblin III (P=0.03). There were no recurrences or delayed complications at the median follow up of 29 months. Conclusion. Shamblin III had a high risk of postoperative neurovascular complications. Therefore, early detection and prompt surgical resection of CBTs will decrease surgical morbidity.

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