Surgical treatment of two patients with infantile spasms in early infancy

hoonchul kang, Da Eun Jung, Kae Min Kim, Yong Soon Hwang, Sang Keun Park, Tae Sung Ko

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Early surgery for catastrophic epilepsy may prevent developmental deterioration and minimize functional deficit resulting from the surgical procedure. We report two patients who had infantile spasms and underwent surgery for epilepsy in early infancy (younger than 6 months old). Magnetic resonance imaging showed cortical dysplasia in both patients. One patient underwent lesionectomy in the right perirolandic area at 49 weeks conceptional age (CA) and the other infant underwent left temporo-occipital disconnection at 45 weeks CA. Both showed Engel classification I and catch-up developmental progress. However, with the second patient, we were concerned about the high volume transfusion relative to her body weight during the extensive disconnection because of the patient's small blood volume. We discuss the benefits and potential risks of surgical treatment for intractable epilepsy in early infancy.

Original languageEnglish
Pages (from-to)453-457
Number of pages5
JournalBrain and Development
Volume28
Issue number7
DOIs
Publication statusPublished - 2006 Aug 1

Fingerprint

Infantile Spasms
Epilepsy
Therapeutics
Malformations of Cortical Development
Blood Volume
Body Weight
Magnetic Resonance Imaging

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

kang, hoonchul ; Jung, Da Eun ; Kim, Kae Min ; Hwang, Yong Soon ; Park, Sang Keun ; Ko, Tae Sung. / Surgical treatment of two patients with infantile spasms in early infancy. In: Brain and Development. 2006 ; Vol. 28, No. 7. pp. 453-457.
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Surgical treatment of two patients with infantile spasms in early infancy. / kang, hoonchul; Jung, Da Eun; Kim, Kae Min; Hwang, Yong Soon; Park, Sang Keun; Ko, Tae Sung.

In: Brain and Development, Vol. 28, No. 7, 01.08.2006, p. 453-457.

Research output: Contribution to journalArticle

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