Symmetrical giant facial plaque-type juvenile xanthogranuloma

A case report with a successful response to fractional CO2 laser treatment

Young In Lee, SangHo Oh

Research output: Contribution to journalArticle

Abstract

Symmetrical giant facial plaque-type juvenile xanthogranuloma (SGFP-JXG) is a rare variant of juvenile xanthogranuloma, reported only in two cases in the literature. We report a case of a 3-year-old Korean boy who developed bilateral yellowish indurated plaques on both cheeks since 1 year after birth. A skin biopsy revealed numerous foam cells and Touton type giant cells throughout the upper dermis, and its immunohistochemical studies resulted positive for CD68 and negative for S-100. The boy was therefore diagnosed as a persistent SGFP-JXG. As the lesion did not show any signs of spontaneous regression, we performed a single session of fractional ablative CO2 laser, which resulted in a significant reduction of the lesion. This is the first case report of a persistent SGFP-JXG on which a single ablative laser therapy was performed with a successful outcome.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalAnnals of Dermatology
Volume31
Issue number2
DOIs
Publication statusPublished - 2019 Jan 1

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Juvenile Xanthogranuloma
Gas Lasers
Foam Cells
Cheek
Laser Therapy
Giant Cells
Therapeutics
Dermis
Parturition
Biopsy
Skin

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

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Symmetrical giant facial plaque-type juvenile xanthogranuloma : A case report with a successful response to fractional CO2 laser treatment. / Lee, Young In; Oh, SangHo.

In: Annals of Dermatology, Vol. 31, No. 2, 01.01.2019, p. 209-212.

Research output: Contribution to journalArticle

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