Synaptic transistors based on a tyrosine-rich peptide for neuromorphic computing

Min Kyu Song, Young Woong Song, Taehoon Sung, Seok Daniel Namgung, Jeong Hyun Yoon, Yoon Sik Lee, Ki Tae Nam, Jang Yeon Kwon

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


In this article, we propose an artificial synaptic device based on a proton-conducting peptide material. By using the redox-active property of tyrosine, the Tyr-Tyr-Ala-Cys-Ala-Tyr-Tyr peptide film was utilized as a gate insulator that shows synaptic plasticity owing to the formation of proton electric double layers. The ion gating effects on the transfer characteristics and temporal current responses are shown. Further, timing-dependent responses, including paired-pulse facilitation, synaptic potentiation, and transition from short-term plasticity to long-term plasticity, have been demonstrated for the electrical emulation of biological synapses in the human brain. Herein, we provide a novel material platform that is bio-inspired and biocompatible for use in brain-mimetic electronic devices.

Original languageEnglish
Pages (from-to)39619-39624
Number of pages6
JournalRSC Advances
Issue number63
Publication statusPublished - 2021 Dec 13

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2020R1A2C2004864).

Publisher Copyright:
© The Royal Society of Chemistry 2021.

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)


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