Synergetic catalytic effect of ionic liquids and ZnO nanoparticles on the selective synthesis of 1,2-disubstituted benzimidazoles using a ball-milling technique

Hemant Sharma, Navneet Kaur, Narinder Singh, Doo Ok Jang

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

A solvent-free selective green synthesis of 1,2-disubstituted benzimidazoles was developed using a ball-milling technique. Recyclable ionic liquid-coated ZnO-nanoparticles (ZnO-NPs, catalyst 5) were employed as a catalyst, which produced high yields, turnover number and turnover frequency because of the synergetic catalytic properties of the ionic liquid and ZnO-NPs. The present method was successfully employed in the synthesis of various 1,2-disubstituted benzimidazole derivatives in excellent yields with high selectivity. The reaction could also be performed on a multi-gram scale with the same efficiency. A high eco-scale score and a low E-factor emphasize the ecofriendly nature of the present method.

Original languageEnglish
Pages (from-to)4263-4270
Number of pages8
JournalGreen Chemistry
Volume17
Issue number8
DOIs
Publication statusPublished - 2015 Aug 1

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Benzimidazoles
Ionic Liquids
Ball milling
Ionic liquids
turnover
catalyst
Nanoparticles
Catalysts
Derivatives
method
ionic liquid
nanoparticle
effect
benzimidazole

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Pollution

Cite this

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abstract = "A solvent-free selective green synthesis of 1,2-disubstituted benzimidazoles was developed using a ball-milling technique. Recyclable ionic liquid-coated ZnO-nanoparticles (ZnO-NPs, catalyst 5) were employed as a catalyst, which produced high yields, turnover number and turnover frequency because of the synergetic catalytic properties of the ionic liquid and ZnO-NPs. The present method was successfully employed in the synthesis of various 1,2-disubstituted benzimidazole derivatives in excellent yields with high selectivity. The reaction could also be performed on a multi-gram scale with the same efficiency. A high eco-scale score and a low E-factor emphasize the ecofriendly nature of the present method.",
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Synergetic catalytic effect of ionic liquids and ZnO nanoparticles on the selective synthesis of 1,2-disubstituted benzimidazoles using a ball-milling technique. / Sharma, Hemant; Kaur, Navneet; Singh, Narinder; Jang, Doo Ok.

In: Green Chemistry, Vol. 17, No. 8, 01.08.2015, p. 4263-4270.

Research output: Contribution to journalArticle

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